Insight into the oxidative stress induced by lead and/or cadmium in blood, liver and kidneys

V Matović, A Buha, D Ðukić-Ćosić, Z Bulat - Food and Chemical Toxicology, 2015 - Elsevier
Besides being important occupational hazards, lead and cadmium are nowadays metals of
great environmental concern. Both metals, without any physiological functions, can induce …

Genotoxic effects of lead: an updated review

J García-Lestón, J Méndez, E Pásaro, B Laffon - Environment international, 2010 - Elsevier
Lead is a ubiquitous toxic heavy metal with unique physical and chemical properties that
make it suitable for a great variety of applications. Because of its high persistence in the …

Protective effects of chrysin against oxidative stress and inflammation induced by lead acetate in rat kidneys: a biochemical and histopathological approach

S Kucukler, F Benzer, S Yildirim, C Gur… - … Trace Element Research, 2021 - Springer
In this study, the protective effects of chrysin (CR) on lead acetate (PbAc)-induced renal
toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and …

Advances in understanding how heavy metal pollution triggers gastric cancer

W Yuan, N Yang, X Li - BioMed research international, 2016 - Wiley Online Library
With the development of industrialization and urbanization, heavy metals contamination has
become a major environmental problem. Numerous investigations have revealed an …

Molecular mechanisms involved in lead uptake, toxicity and detoxification in higher plants

B Pourrut, M Shahid, F Douay, C Dumat… - Heavy metal stress in …, 2013 - Springer
Lead (Pb) is one of the most useful metals, and has contaminated most of the ecosystems. It
has been known to influence various morphological, physiological and biochemical …

Ternary dinuclear copper (II) complexes of a hydroxybenzamide ligand with diimine coligands: the 5, 6-dmp ligand enhances DNA binding and cleavage and induces …

S Ramakrishnan, D Shakthipriya, E Suresh… - Inorganic …, 2011 - ACS Publications
The dinuclear copper (II) complexes [Cu2 (LH) 2 (diimine) 2 (ClO4) 2](ClO4) 2 (1–4), where
LH= 2-hydroxy-N-[2-(methylamino) ethyl] benzamide and diimine= 2, 2′-bipyridine (bpy; 1) …

Toward the development of metal-based synthetic nucleases: DNA binding and oxidative DNA cleavage of a mixed copper (II) complex with N-(9H-purin-6-yl) …

JL García-Giménez, M González-Álvarez… - Journal of inorganic …, 2009 - Elsevier
The complex [Cu (N9-ABS)(phen) 2]· 3.6 H2O, H2N9-ABS= N-(9H-purin-6-yl)
benzenesulfonamide and phen= 1, 10-phenanthroline, has been synthesized and then …

Carnosine and histidine supplementation blunt lead-induced reproductive toxicity through antioxidative and mitochondria-dependent mechanisms

MM Ommati, A Jamshidzadeh, R Heidari, Z Sun… - Biological trace element …, 2019 - Springer
Lead (Pb)-induced reproductive toxicity is a well-characterized adverse effect associated
with this heavy metal. It has been found that Pb exposure is associated with altered …

Lead-induced DNA damage in Vicia faba root cells: potential involvement of oxidative stress

B Pourrut, S Jean, J Silvestre, E Pinelli - Mutation Research/Genetic …, 2011 - Elsevier
Genotoxic effects of lead (0–20μM) were investigated in whole-plant roots of Vicia faba L.,
grown hydroponically under controlled conditions. Lead-induced DNA damage in V. faba …

Quercetin protects rat liver against lead-induced oxidative stress and apoptosis

CM Liu, YL Zheng, J Lu, ZF Zhang, SH Fan… - Environmental …, 2010 - Elsevier
Quercetin, a flavonoid, effectively improved the lead-induced histology changes including
structure damage and leukocyte infiltration in rat liver. The present study was designed to …