Spinal dura mater: biophysical characteristics relevant to medical device development
Understanding the relevant biophysical properties of the spinal dura mater is essential to the
design of medical devices that will directly interact with this membrane or influence the …
design of medical devices that will directly interact with this membrane or influence the …
Intrathecal therapeutics: device design, access methods, and complication mitigation
Introduction The intrathecal space remains underutilized for diagnostic testing, invasive
monitoring or as a pipeline for the delivery of neurological therapeutic agents and devices …
monitoring or as a pipeline for the delivery of neurological therapeutic agents and devices …
Kinematic analysis of the gait of adult sheep during treadmill locomotion: parameter values, allowable total error, and potential for use in evaluating spinal cord injury
S Safayi, ND Jeffery, SK Shivapour… - Journal of the …, 2015 - Elsevier
We are developing a novel intradural spinal cord (SC) stimulator designed to improve the
treatment of intractable pain and the sequelae of SC injury. In-vivo ovine models of …
treatment of intractable pain and the sequelae of SC injury. In-vivo ovine models of …
Intradural spinal cord stimulation: performance modeling of a new modality
Introduction: Intradural spinal cord stimulation (SCS) may offer significant therapeutic
benefits for those with intractable axial and extremity pain, visceral pain, spasticity …
benefits for those with intractable axial and extremity pain, visceral pain, spasticity …
Postsurgical pathologies associated with intradural electrical stimulation in the central nervous system: design implications for a new clinical device
Spinal cord stimulation has been utilized for decades in the treatment of numerous
conditions such as failed back surgery and phantom limb syndromes, arachnoiditis, cancer …
conditions such as failed back surgery and phantom limb syndromes, arachnoiditis, cancer …
Revisiting intradural spinal cord stimulation: an introduction to a novel intradural spinal cord stimulation device
BD Dalm, SV Viljoen, NS Dahdaleh… - Innovative …, 2014 - degruyter.com
Background: Spinal cord stimulation has been in use for decades and is growing as a
therapeutic treatment option. A significant problem arising from the epidural location of the …
therapeutic treatment option. A significant problem arising from the epidural location of the …
Contemporary approaches to preventing and treating infections of novel intrathecal neurostimulation devices
Introduction Contemporary approaches to surgical site infections have evolved significantly
over the last several decades in response to the economic pressures of soaring health care …
over the last several decades in response to the economic pressures of soaring health care …
Biomechanical performance of an ovine model of intradural spinal cord stimulation
S Safayi, ND Jeffery, DC Fredericks… - Journal of medical …, 2014 - Taylor & Francis
The authors are developing a novel type of spinal cord stimulator, designed to be placed
directly on the pial surface of the spinal cord, for more selective activation of target tissues …
directly on the pial surface of the spinal cord, for more selective activation of target tissues …
Durotomy surrogate and seals for intradural spinal cord stimulators: apparatus and review of clinical methods and materials
Introduction We are developing a novel intradural spinal cord stimulator for treatment of
neuropathic pain and spasticity. A key feature is the means by which it seals the dura mater …
neuropathic pain and spasticity. A key feature is the means by which it seals the dura mater …
Finite-element study of the performance characteristics of an intradural spinal cord stimulator
NM Grosland, GT Gillies… - Journal of …, 2014 - asmedigitalcollection.asme.org
We have used finite-element (FE) modeling to investigate the mechanical compliance,
positional stability and contact pressures associated with a novel type of spinal cord …
positional stability and contact pressures associated with a novel type of spinal cord …