Reactive oxygen and nitrogen species: impact on endothelial dysfunction

D Salisbury, U Bronas - Nursing research, 2015 - journals.lww.com
Background Reactive oxygen and nitrogen species, known as free radicals, play a key role
in the etiology and progression of atherosclerotic cardiovascular disease by creating …

Reversal and remission of T2DM–An update for practitioners

L Shibib, M Al-Qaisi, A Ahmed, AD Miras… - Vascular Health and …, 2022 - Taylor & Francis
Over the past 50 years, many countries around the world have faced an unchecked
pandemic of obesity and type 2 diabetes (T2DM). As best practice treatment of T2DM has …

Effects of high-intensity interval training and moderate-intensity continuous training on glycaemic control and skeletal muscle mitochondrial function in db/db mice

V Chavanelle, N Boisseau, YF Otero, L Combaret… - Scientific reports, 2017 - nature.com
Physical activity is known as an effective strategy for prevention and treatment of Type 2
Diabetes. The aim of this work was to compare the effects of a traditional Moderate Intensity …

The role of pre-existing diabetes mellitus on hepatocellular carcinoma occurrence and prognosis: a meta-analysis of prospective cohort studies

WS Yang, P Va, F Bray, S Gao, J Gao, HL Li, YB Xiang - PloS one, 2011 - journals.plos.org
Background The impact of pre-existing diabetes mellitus (DM) on hepatocellular carcinoma
(HCC) occurrence and prognosis is complex and unclear. The aim of this meta-analysis is to …

Telomere length maintenance and cardio-metabolic disease prevention through exercise training

J Denham, BJ O'Brien, FJ Charchar - Sports medicine, 2016 - Springer
Telomeres are tandem repeat DNA sequences located at distal ends of chromosomes that
protect against genomic DNA degradation and chromosomal instability. Excessive telomere …

Effect of 12-week resistance exercise program on body composition, muscle strength, physical function, and glucose metabolism in healthy, insulin-resistant, and …

OG Geirsdottir, A Arnarson, K Briem… - … Series A: Biomedical …, 2012 - academic.oup.com
Background. Insulin is a stimulator of skeletal muscle protein anabolism and insulin
resistance might therefore negatively affect muscle protein metabolism. We investigated …

Prevalence and correlates of diagnosed and undiagnosed type 2 diabetes mellitus and pre-diabetes in older adults: Findings from the Irish Longitudinal Study on …

S Leahy, AM O'Halloran, N O'Leary, M Healy… - Diabetes research and …, 2015 - Elsevier
Aims The prevalence of type 2 diabetes and pre-diabetes has increased rapidly in recent
decades and this trend will continue as the global population ages. This study investigates …

A fuzzy cognitive map of the psychosocial determinants of obesity

PJ Giabbanelli, T Torsney-Weir, VK Mago - Applied soft computing, 2012 - Elsevier
Two thirds of American adults are now obese or overweight, and this proportion continues to
increase. Primary care doctors are placed at the front lines in addressing the obesity …

Environmental enrichment ameliorated high-fat diet-induced Aβ deposition and memory deficit in APP transgenic mice

M Maesako, K Uemura, M Kubota, A Kuzuya… - Neurobiology of …, 2012 - Elsevier
The pathogenesis of Alzheimer's disease (AD) is tightly associated with metabolic
dysfunctions. In particular, a potential link between type 2 diabetes (T2DM) and AD has …

Leisure activity and social integration mitigate the risk of dementia related to cardiometabolic diseases: a population‐based longitudinal study

Z Wang, A Marseglia, Y Shang, C Dintica… - Alzheimer's & …, 2020 - Wiley Online Library
Introduction The effect of comorbid cardiometabolic diseases (CMDs), including diabetes,
heart diseases, and stroke, on dementia remains unclear. Methods A cohort of 2648 …