Schizophrenia is a life-shortening disease and life expectancy in patients may be 15–20
years shorter than in the general population, with increasing longevity gap over time …

Cognitive impairment is a shared abnormality between type 2 diabetes mellitus (T2DM) and
many neurodegenerative and neuropsychiatric disorders, such as Alzheimer's disease (AD) …

The high prevalence of metabolic syndrome in persons with schizophrenia has spurred
investigational efforts to study the mechanism beneath its pathophysiology. Early psychosis …

AimsCardiometabolic diseases are responsible for the majority of premature deaths in
people with schizophrenia. This study aimed to quantify the fatal burden of ischaemic heart …

Introduction Both type 2 diabetes mellitus (T2DM) and schizophrenia are known to be
associated with cognitive deficits. The impact of the comorbidities of T2DM or prediabetes …

The presence of a pro-oxidant state in patients with schizophrenia may account for the
increased risk of atherosclerosis and cardiovascular disease in this group and supports the …

Metabolic disorders (MDs) like obesity, dyslipidemia, and type 2 diabetes are more
frequently observed in patients diagnosed with psychiatric disorders undergoing treatment …

Abstract Background Previous studies on European (EUR) samples have obtained
inconsistent results regarding the genetic correlation between type 2 diabetes mellitus …

Schizophrenia is one of the most serious psychiatric disorders and is characterized by
reductions in both brain volume and spine density in the frontal cortex. RhoA belongs to the …

The melanocortin receptors are G-protein-coupled receptors, which are essential
components of the hypothalamic–pituitary–adrenal axis, and they mediate the actions of …