HIF is a transcription factor that plays an essential role in the cellular response to low
oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In …

Purpose Invasive pulmonary aspergillosis has been increasingly recognized in COVID-19
patients, termed COVID-19-associate pulmonary aspergillosis (CAPA). Our meta-analysis …

Background Invasive pulmonary aspergillosis typically occurs in an immunocompromised
host. For almost a century, influenza has been known to set up for bacterial superinfections …

Abstract Coronavirus disease 2019 (COVID-19) can become complicated by secondary
invasive fungal infections (IFIs), stemming primarily from severe lung damage and …

Opportunistic fungal infections have high mortality in patients with severe immune
dysfunction. Growing evidence suggests that the immune environment of invasive fungal …

The COVID-19 pandemic has placed a huge strain on global healthcare and been a
significant cause of increased morbidity and mortality, particularly in at-risk populations. This …

Solid tumors grow at a high speed leading to insufficient blood supply to tumor cells. This
makes the tumor hypoxic, resulting in the Warburg effect and an increased generation of …

Bronchiectasis is a chronic airway infection syndrome, distinct from cystic fibrosis that is
rising in prevalence and is associated with significant morbidity and mortality. It can be …

Background Invasive pulmonary aspergillosis is increasingly identified as a complication of
influenza, termed 'influenza-associated pulmonary aspergillosis'(IAPA). Aims To assess the …

Aspergillus fumigatus spores initiate more than 3,000,000 chronic and 300,000 invasive
diseases annually, worldwide. Depending on the immune status of the host, inhalation of …