Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA
sequence. These epigenetic factors include DNA methylation, acetylation of histones and …

Familial porencephaly, leukoencephalopathy and small-vessel disease belong to the
spectrum of disorders ascribed to dominant mutations in the gene encoding for type IV …

The location of an acute ischemic stroke is associated with its prognosis. The widely used
Gaussian model-based parameter, apparent diffusion coefficient (ADC), cannot reveal …

Mutations in the gene encoding phosphodiesterase 4D (PDE4D) enzyme are associated
with ischemic stroke; however the functional implications of such mutations are not well …

Little is known about the epigenetic changes associated with delayed cerebral ischemia
(DCI) pathogenesis after subarachnoid hemorrhage (SAH). Here, we investigated genome …

Ischemic stroke (IS) is one of the most common cerebrovascular diseases worldwide. The
aberrant expression of BCL6 has been previously implicated in the pathogenesis of IS …

MicroRNAs are endogenous non-coding RNAs about 22 nucleotides in length that can
repress the expression of proteins by binding to the 3′-untranslated regions of target …

Background: Variants in the 5-lipoxygenase-activating protein (ALOX5AP) and
phosphodiesterase 4D (PDE4D) genes have first been associated with ischemic stroke (IS) …

Introducción. El ataque cerebrovascular (ACV) es una entidad nosológica, que además de
producir diferentes déficits funcionales y estructurales, origina diversos tipos de limitaciones …

BACKGROUND: CYP4F2 is a member of the cytochrome P450 enzymes and is responsible
for metabolizing arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE); 20-HETE …