Long non-coding RNA: Classification, biogenesis and functions in blood cells

S Dahariya, I Paddibhatla, S Kumar… - Molecular …, 2019 - Elsevier
While there exist some long non-coding RNAs (lncRNAs) that are structurally similar to
mRNAs (capped, spliced, poly a tail), not all of the lncRNAs exhibit these features …

Long noncoding RNAs as biomarkers in cancer

L Bolha, M Ravnik-Glavač, D Glavač - Disease markers, 2017 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a relatively well‐characterized class of noncoding
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …

Molecular mechanisms of apoptosis and roles in cancer development and treatment

S Goldar, MS Khaniani, SM Derakhshan… - Asian Pacific journal …, 2015 - koreascience.kr
Programmed cell death (PCD) or apoptosis is a mechanism which is crucial for all
multicellular organisms to control cell proliferation and maintain tissue homeostasis as well …

Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides

KA Lennox, MA Behlke - Nucleic acids research, 2016 - academic.oup.com
Thousands of long non-coding RNAs (lncRNAs) have been identified in mammalian cells.
Some have important functions and their dysregulation can contribute to a variety of disease …

[HTML][HTML] Long noncoding RNAs in cancer: mechanisms of action and technological advancements

N Bartonicek, JLV Maag, ME Dinger - Molecular cancer, 2016 - Springer
The previous decade has seen long non-coding RNAs (lncRNAs) rise from obscurity to
being defined as a category of genetic elements, leaving its mark on the field of cancer …

Basic biology and therapeutic implications of lncRNA

O Khorkova, J Hsiao, C Wahlestedt - Advanced drug delivery reviews, 2015 - Elsevier
Long non-coding RNAs (lncRNA), a class of non-coding RNA molecules recently identified
largely due to the efforts of FANTOM, and later GENCODE and ENCODE consortia, have …

TUG 1: a pivotal oncogenic long non‐coding RNA of human cancers

Z Li, J Shen, MTV Chan, WKK Wu - Cell proliferation, 2016 - Wiley Online Library
Long non‐coding RNA s (lnc RNA s) are a group greater than 200 nucleotides in length. An
increasing number of studies has shown that lnc RNA s play important roles in diverse …

Long non-coding RNAs as epigenetic regulators in cancer

A Vafadar, Z Shabaninejad… - Current …, 2019 - ingentaconnect.com
Long noncoding RNAs (lncRNAs) constitute large portions of the mammalian transcriptome
which appeared as a fundamental player, regulating various cellular mechanisms. LncRNAs …

Long noncoding RNAs in cancer cells

DH Bach, SK Lee - Cancer letters, 2018 - Elsevier
Long noncoding RNA (lncRNA) has recently been investigated as key modulators that
regulate many biological processes in human cancers via diverse mechanisms. LncRNAs …

[HTML][HTML] The role of LncRNAs in translation

D Karakas, B Ozpolat - Non-coding RNA, 2021 - mdpi.com
Long non-coding RNAs (lncRNAs), a group of non-protein coding RNAs with lengths of
more than 200 nucleotides, exert their effects by binding to DNA, mRNA, microRNA, and …