Biological therapies for the treatment of Behçet's disease-related uveitis beyond TNF-alpha blockade: a narrative review

J Sota, D Rigante, G Lopalco, B Frediani… - Rheumatology …, 2018 - Springer
Intraocular inflammation is one of the more relevant complications of Behçet's disease (BD),
which tends to respond poorly to different medications. The ocular histopathologic changes …

[HTML][HTML] A review of systemic biologics and local immunosuppressive medications in uveitis

NS Mehta, P Emami-Naeini - Journal of ophthalmic & vision …, 2022 - ncbi.nlm.nih.gov
Uveitis is one of the most common causes of vision loss and blindness worldwide. Local
and/or systemic immunosuppression is often required to treat ocular inflammation in …

Management of severe complications in Behçet's disease with TNF inhibitors

AC Desbois, H Vallet, F Domont… - Expert Opinion on …, 2017 - Taylor & Francis
Introduction: The efficacy of anti-TNFα agents has been recently evaluated in many studies
in Behçet's disease (BD), particularly in ocular and life-threatening manifestations such as …

Biologic therapy in large and small vessels vasculitis, and Behçet's disease: Evidence-and practice-based guidance

JA Correia, J Crespo, G Alves, F Salvador… - Autoimmunity …, 2023 - Elsevier
Objective Vasculitis are a very heterogenous group of systemic autoimmune diseases,
affecting large vessels (LVV), small vessels or presenting as a multisystemic variable vessel …

Effectiveness and safety of interferon α2a as an add-on treatment for refractory Behçet's uveitis

J Shi, C Zhao, J Zhou, J Liu, L Wang… - … in Chronic Disease, 2019 - journals.sagepub.com
Objective: The objective of this study was to investigate the effectiveness and safety of
interferon (IFN) α2a as an add-on treatment for refractory Behçet's uveitis (BU). Methods: In …

[PDF][PDF] Efficacy of anti-tumour necrosis factor-α monoclonal antibodies in patients with non-infectious anterior uveitis

C Fabiani, A Vitale, D Rigante, G Emmi… - Clin Exp …, 2019 - clinexprheumatol.org
Objective. To assess the efficacy of monoclonal anti-tumour necrosis factor (TNF)-α agents
in patients with anterior uveitis (AU) in terms of decrease of recurrences, variation of visual …

[PDF][PDF] Epidemiological profile of non-infectious uveitis from the rheumatologist's perspective: a survey from two tertiary referral centres in Italy

G Lopalco, V Venerito, J Sota, D Rigante… - Clin Exp …, 2018 - clinexprheumatol.org
Objective. To describe the epidemiology of non-infectious uveitis (NIU) in two tertiary referral
rheumatology units in Central and Southern Italy. Methods. Two hundred and seventyeight …

[HTML][HTML] Advances in pathogenesis and treatment of ocular involvement in Behcet's disease

S Lin, Z Xu, Z Lin, B Xie, J Feng - Frontiers in Immunology, 2023 - frontiersin.org
Behcet's disease (BD) is a chronic multi-systemic disease characterized by relapsing-
remitting oral ulcers, genital ulcers, ocular inflammatory involvements, and numerous other …

Adalimumab rapidly controls both anterior and posterior inflammation in patients with ocular Behçet syndrome and non-infectious uveitis refractory to conventional …

C Evereklioglu, HK Sonmez, DG Sevim, H Arda… - International …, 2023 - Springer
Purpose To evaluate the efficacy and safety of adalimumab (ADA, Humira®) for treatment of
non-infectious uveitis (NIU) refractory to conventional medications. Methods Anti-tumor …

Systemic steroid sparing effect of intravitreal dexamethasone implant in chronic noninfectious uveitic macular edema

C Fabiani, A Vitale, G Emmi, G Lopalco… - Journal of Ocular …, 2017 - liebertpub.com
Purpose: To evaluate the effectiveness and the systemic corticosteroid sparing effect of a
single intravitreal dexamethasone (DEX) implant in patients with chronic noninfectious …