Sex differences in blood pressure regulation and hypertension: renal, hemodynamic, and hormonal mechanisms

ER Drury, J Wu, JC Gigliotti, TH Le - Physiological Reviews, 2024 - journals.physiology.org
The teleology of sex differences has been argued since at least as early as Aristotle's
controversial Generation of Animals more than 300 years BC, which reflects the sex bias of …

[HTML][HTML] Fetal programming and cardiovascular pathology

BT Alexander, JH Dasinger… - Comprehensive Physiology, 2015 - ncbi.nlm.nih.gov
Low birth weight serves as a crude proxy for impaired growth during fetal life and indicates a
failure for the fetus to achieve its full growth potential. Low birth weight can occur in …

Is low birth weight an antecedent of CKD in later life? A systematic review of observational studies

SL White, V Perkovic, A Cass, CL Chang… - American Journal of …, 2009 - Elsevier
BACKGROUND: There has been considerable interest in the hypothesis that low birth
weight may be a marker of impaired nephrogenesis and that this is causally related to …

The clinical importance of nephron mass

VA Luyckx, BM Brenner - Journal of the American Society of …, 2010 - journals.lww.com
Abundant evidence supports the association between low birth weight (LBW) and renal
dysfunction in humans. Anatomic measurements of infants, children, and adults show …

Maternal undernutrition during early to mid-gestation in the ewe results in altered growth, adiposity, and glucose tolerance in male offspring

SP Ford, BW Hess, MM Schwope… - Journal of animal …, 2007 - academic.oup.com
This study utilized maternal undernutrition from early to midgestation in the ewe to determine
the impact (s) of intrauterine growth restriction on postpartum growth of male offspring and …

Developmental origins of adult disease

SC Langley-Evans, S McMullen - Medical principles and practice, 2010 - karger.com
Variation in the quality or quantity of nutrients consumed during pregnancy can exert
permanent and powerful effects upon the developing fetus. This programming of fetal …

Targeting the renin–angiotensin–aldosterone system to prevent hypertension and kidney disease of developmental origins

CN Hsu, YL Tain - International Journal of Molecular Sciences, 2021 - mdpi.com
The renin-angiotensin-aldosterone system (RAAS) is implicated in hypertension and kidney
disease. The developing kidney can be programmed by various early-life insults by so …

The good, the bad, and the ugly of pregnancy nutrients and developmental programming of adult disease

CN Hsu, YL Tain - Nutrients, 2019 - mdpi.com
Maternal nutrition plays a decisive role in developmental programming of many non-
communicable diseases (NCDs). A variety of nutritional insults during gestation can cause …

Adult sequelae of intrauterine growth restriction

MG Ross, MH Beall - Seminars in perinatology, 2008 - Elsevier
Fetal intrauterine growth restriction has been associated with adult disease in both human
epidemiologic studies and in animal models. In some cases, intrauterine deprivation …

Fetal programming of hypertension

BT Alexander - American Journal of Physiology-Regulatory …, 2006 - journals.physiology.org
Numerous epidemiological studies suggest an inverse relationship between low birth weight
(LBW) and hypertension, an observation now supported by numerous animal studies. The …