A guide to designing photocontrol in proteins: methods, strategies and applications

AC Kneuttinger - Biological Chemistry, 2022 - degruyter.com
Light is essential for various biochemical processes in all domains of life. In its presence
certain proteins inside a cell are excited, which either stimulates or inhibits subsequent …

Triplet‐Triplet Annihilation Upconversion‐Based Photolysis: Applications in Photopharmacology

M Klimezak, J Chaud, A Brion, F Bolze… - Advanced …, 2024 - Wiley Online Library
The emerging field of photopharmacology is a promising chemobiological methodology for
optical control of drug activities that could ultimately solve the off‐target toxicity outside the …

Photoactivatable Liposomes for Blue to Deep Red Light-Activated Surface Drug Release: Application to Controlled Delivery of the Antitumoral Drug Melphalan

A Brion, J Chaud, M Klimezak, F Bolze… - Bioconjugate …, 2023 - ACS Publications
Liposome-based nanoparticles able to release, via a photolytic reaction, a payload
anchored at the surface of the phospholipid bilayer were prepared. The liposome …

Two-Photon Sensitive Coumarinyl Photoremovable Protecting Groups with Rigid Electron-Rich Cycles Obtained by Domino Reactions Initiated by a 5-exo-Dig …

J Chaud, C Morville, F Bolze, D Garnier… - Organic …, 2021 - ACS Publications
We herein report the design, synthesis, and photophysical characterization of extended and
rigid coumarinyl derivatives showing large two-photon sensitivities (δaΦu≤ 125 GM) at 740 …

Towards a Light‐mediated Gene Therapy for the Eye using Caged Ethinylestradiol and the Inducible Cre/lox System

Z Kiy, J Chaud, L Xu, E Brandhorst… - Angewandte …, 2024 - Wiley Online Library
Increasingly, retinal pathologies are being treated with virus‐mediated gene therapies. To
be able to target viral transgene expression specifically to the pathological regions of the …

A Blue Light and Two‐Photon Activatable Rhodamine Fluorophore

R Weber, S Junek, A Heckel - Chemistry–A European Journal, 2023 - Wiley Online Library
Photoactivatable fluorophores (PAFs) are powerful tools for biological imaging applications
because they provide spatiotemporal control of fluorescence distribution. Many of the …

Ultrafast and efficient energy transfer in a one-and two-photon sensitized rhodamine-BODIPY dyad: a perspective for broadly absorbing photocages

M Asido, C Hamerla, R Weber, M Horz… - Physical Chemistry …, 2022 - pubs.rsc.org
In view of the demand for photoactivatable probes that operate in the visible (VIS) to near
infrared (NIR) region of the spectrum, we designed a bichromophoric system based on a …

Triphenylamine Sensitized 8‐Dimethylaminoquinoline: An Efficient Two‐Photon Caging Group for Intracellular Delivery

PI Dalko, D Rigault, P Nizard, J Daniel… - … –A European Journal - Wiley Online Library
Triphenylamine‐sensitized 8‐dimethylaminoquinoline (TAQ) probes showed fair two‐
photon absorption and fragmentation cross sections in releasing kainate and GABA ligands …

Phototheranostics: Combining Targeting, Imaging, Therapy

AP Demchenko - Introduction to Fluorescence Sensing: Volume 2 …, 2023 - Springer
Phototheranostics is a new revolutionary trend in medicine that allows operating with light
beams to provide destroying or healing the targeted cells and tissues by controlled thermal …

[PDF][PDF] ИССЛЕДОВАНИЕ СПЕКТРАЛЬНО-КИНЕТИЧЕСКИХ ХАРАКТЕРИСТИК И ЗАКОНОМЕРНОСТЕЙ ФОТОХИМИЧЕСКИХ ПРОЦЕССОВ С УЧАСТИЕМ …

АЕ ЕГОРОВ - biochemphysics.ru
Фотосенсибилизаторы (ФС) находят применение для лечения некоторых опухолевых
заболеваний методом фотодинамической терапии (ФДТ)[1]. В результате поглощения …