Advances in the study of heart development and disease using zebrafish

DR Brown, LA Samsa, L Qian, J Liu - Journal of cardiovascular …, 2016 - mdpi.com
Animal models of cardiovascular disease are key players in the translational medicine
pipeline used to define the conserved genetic and molecular basis of disease. Congenital …

Nanoplastics decrease the toxicity of a complex PAH mixture but impair mitochondrial energy production in developing zebrafish

R Trevisan, C Voy, S Chen… - Environmental science & …, 2019 - ACS Publications
Plastics are recognized as a worldwide threat to the environment, possibly affecting human
health and wildlife. Small forms of plastics such as micro-and nanoplastics can interact with …

Impacts of petroleum-derived pollutants on fish development

GN Cherr, E Fairbairn… - Annual review of animal …, 2017 - annualreviews.org
The teleost fish embryo is particularly sensitive to petroleum hydrocarbons (polycyclic
aromatic hydrocarbons, PAHs) at two distinct stages of development. The first is early during …

Polycyclic aromatic hydrocarbons (PAHs) in indoor environments are still imposing carcinogenic risk

M Wang, S Jia, SH Lee, A Chow, M Fang - Journal of Hazardous Materials, 2021 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are among the most health-relevant air pollutants.
Herein, we conducted meta-analysis and experimental validation to evaluate PAHs in our …

PAH sorption to nanoplastics and the Trojan horse effect as drivers of mitochondrial toxicity and PAH localization in zebrafish

R Trevisan, D Uzochukwu, RT Di Giulio - Frontiers in environmental …, 2020 - frontiersin.org
Plastics are world-wide pollutants that pose a potential threat to wildlife and human health.
Small plastic particles, such as microplastics and nanoplastics, are easily ingested, and can …

Metabolomic and transcriptomic analysis of MCF-7 cells exposed to 23 chemicals at human-relevant levels: estimation of individual chemical contribution to effects

M Liu, S Jia, T Dong, F Zhao, T Xu… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Humans are constantly being exposed to various xenobiotics at relatively low
concentrations. To date, limited evidence is available to ascertain whether a complex …

Aryl hydrocarbon receptor activation and developmental toxicity in zebrafish in response to soil extracts containing unsubstituted and oxygenated PAHs

E Wincent, ME Jonsson, M Bottai… - … science & technology, 2015 - ACS Publications
Many industrial sites are polluted by complex mixtures of polycyclic aromatic compounds
(PACs). Besides polycyclic aromatic hydrocarbons (PAHs), these mixtures often contain …

Occupational inhalation exposures to nanoparticles at six Singapore printing centers

MI Setyawati, D Singh, SPR Krishnan… - … science & technology, 2020 - ACS Publications
Laser printers emit high levels of nanoparticles (PM0. 1) during operation. Although it is well
established that toners contain multiple engineered nanomaterials (ENMs), little is known …

Halogenated carbazoles induce cardiotoxicity in developing zebrafish (Danio rerio) embryos

M Fang, J Guo, D Chen, A Li… - Environmental …, 2016 - Wiley Online Library
Halogenated carbazoles are increasingly identified as a novel class of environmental
contaminants. However, no in vivo acute toxicity information on those compounds was …

Recent advances in sampling and sample preparation for effect-directed environmental analysis

S Huang, M Fan, N Wawryk, J Qiu, X Yang… - TrAC Trends in …, 2022 - Elsevier
Complex chemicals have been imposing adverse effects on the environment and
organisms. Conventional chemical-based quantitative analysis may not comprehensively …