Elegant Nematodes Improve Our Understanding of Human Neuronal Diseases, the Role of Pollutants and Strategies of Resilience

A von Mikecz - Environmental Science & Technology, 2023 - ACS Publications
The prevalence of neurodegenerative disorders such as Alzheimer's and Parkinson's
disease are rising globally. The role of environmental pollution in neurodegeneration is …

[HTML][HTML] Anti-aging effects of medicinal plants and their rapid screening using the nematode Caenorhabditis elegans

X Chen, F Bahramimehr, N Shahhamzehei, H Fu, S Lin… - Phytomedicine, 2024 - Elsevier
Background Aging is the primary risk factor of most chronic diseases in humans, including
cardiovascular diseases, osteoporosis and neurodegenerative diseases, which extensively …

The Bacterial Gq Signal Transduction Inhibitor FR900359 Impairs Soil-Associated Nematodes

W Hanke, J Alenfelder, J Liu, P Gutbrod… - Journal of chemical …, 2023 - Springer
The cyclic depsipeptide FR900359 (FR) is derived from the soil bacterium Chromobacterium
vaccinii and known to bind Gq proteins of mammals and insects, thereby abolishing the …

Mitochondrial energy state controls AMPK-mediated foraging behavior in C. elegans

A Vodičková, A Müller-Eigner, CN Okoye… - Science …, 2024 - science.org
Organisms surveil and respond to their environment using behaviors entrained by metabolic
cues that reflect food availability. Mitochondria act as metabolic hubs and at the center of …

HLH-30/TFEB mediates sexual dimorphism in immunity in Caenorhabditis elegans

J Sohn, S Kwon, GY Lee, SS Kim, Y Lee, J Lee… - Autophagy, 2024 - Taylor & Francis
Sexual dimorphism affects various biological functions, including immune responses.
However, the mechanisms by which sex alters immunity remain largely unknown. Using …

Adapting and optimizing GCaMP8f for use in Caenorhabditis elegans

J Liu, E Bonnard, M Scholz - Genetics, 2024 - academic.oup.com
Improved genetically encoded calcium indicators (GECIs) are essential for capturing
intracellular dynamics of both muscle and neurons. A novel set of GECIs with ultrafast …

C. elegans foraging as a model for understanding the neuronal basis of decision-making

JA Haley, SH Chalasani - Cellular and Molecular Life Sciences, 2024 - Springer
Animals have evolved to seek, select, and exploit food sources in their environment.
Collectively termed foraging, these ubiquitous behaviors are necessary for animal survival …

Fantastic beasts and how to study them: rethinking experimental animal behavior

SS Ding, JL Fox, A Gordus, A Joshi… - Journal of …, 2024 - journals.biologists.com
Humans have been trying to understand animal behavior at least since recorded history.
Recent rapid development of new technologies has allowed us to make significant progress …

[PDF][PDF] The Bacterial G

SA Nematodes - Journal of Chemical Ecology, 2023 - scienceopen.com
The cyclic depsipeptide FR900359 (FR) is derived from the soil bacterium Chromobacterium
vaccinii and known to bind Gq proteins of mammals and insects, thereby abolishing the …

Predatory aggression evolved through adaptations to noradrenergic circuits

GG Eren, L Boger, M Roca, F Hiramatsu, J Liu… - bioRxiv, 2024 - biorxiv.org
Behaviors are adaptive traits evolving through natural selection. Crucially, the genetic,
molecular, and neural modifications that shape behavioral innovations are poorly …