The past decades have witnessed great progress in cancer immunotherapy, which has
profoundly revolutionized oncology, whereas low patient response rates and potential …

Acute inflammation is essential for initiating and coordinating the body's response to injuries
and infections. However, in acute inflammatory diseases, inflammation is not resolved but …

Immunotherapy has emerged as an eminent and effective modality in the treatment of
cancer. However, current cancer immunotherapies lack spatial and temporal control …

The development of precise and personalized medicine requires novel formulation
strategies to deliver the therapeutic payloads to the pathological tissues, producing …

Nanomaterials and targeted drug delivery vehicles improve the therapeutic index of drugs
and permit greater control over their pharmacokinetics, biodistribution, and bioavailability …

Abstract 3D bioprinting is an advanced technology combining cells and bioactive molecules
within a single bioscaffold; however, this scaffold cannot change, modify or grow in response …

Nowadays, immunotherapy is one of the most essential treatments for various diseases and
a broad spectrum of disorders are assumed to be treated by altering the function of the …

With the rapid development of nanotechnology, strategies related to nanomedicine have
been used to overcome the shortcomings of traditional chemotherapy drugs, thereby …

Succinate is an important metabolite that modulates metabolism of immune cells and cancer
cells in the tumor microenvironment (TME). Herein, we report that polyethylene succinate …

Although different metabolic pathways have been associated with distinct macrophage
phenotypes, the field of utilizing metabolites to modulate macrophage phenotype is in a …