The most common cause of acquired thyroid dysfunction is autoimmune thyroid disease,
which is an organ-specific autoimmune disease with two presentation phenotypes …

Simple Summary CD40 is a costimulatory molecule that is key for the activation of antigen-
presenting cells and other innate immune cells. It plays an important role in anti-tumor …

Highlights CD40 expression correlates with the type I anti-tumor response and better
survival. Pan-cancer bioinformatics characterization reveals reduced CD40 expression in 11 …

During the last two decades, an increasing number of reports have pointed out that the
immunogenicity of polyethylene glycol (PEG) may trigger accelerated blood clearance …

Hidradenitis suppurativa (HS) is a chronic, recurrent, auto-inflammatory skin disease
originating from the hair follicles. The typical inflammatory nodules, abscesses, and draining …

Chronic inflammation drives the development of atherosclerosis. Despite optimal treatment
of classical cardiovascular risk factors, a substantial portion of the population has elevated …

The CD40–CD40 ligand (CD40L) dyad represents a scientific and clinical field that has
raised many controversies in the past and cannot be clearly defined as being an either …

Introduction Despite numerous efforts to describe COVID-19's immunological landscape,
there is still a gap in our understanding of the virus's infections after-effects, especially in the …

The complex structure of the tumor microenvironment leads to the poor efficacy of tumor
immunotherapy. The therapeutic adjuvant designed to enhance the effect of T cells by acting …

Dysregulated activation of polyclonal B cells and production of pathogenic antibodies are
involved in the development of rheumatoid arthritis (RA). Therefore, targeted B cell therapy …