Dyrk1a Phosphorylation of α‐Synuclein Mediating Apoptosis of Dopaminergic Neurons in Parkinson's Disease

Y Yong, Q Wu, X Meng, R Lu, H Xia, F Pei… - Parkinson's …, 2023 - Wiley Online Library
Objective. To investigate the role of aberrant Dyrk1a expression in phosphorylation
modification at the α‐synuclein serine 129 (Ser129) site to analyze its molecular mechanism …

Dietary supplementation with probiotics promotes weight loss by reshaping the gut microbiome and energy metabolism in obese dogs

A Kang, MJ Kwak, DJ Lee, JJ Lee, MK Kim… - Microbiology …, 2024 - Am Soc Microbiol
Obesity and overweight among companion animals are significant concerns, paralleling the
issues observed in human populations. Recent research has highlighted the potential …

Pyruvate is modified by tea/coffee metabolites and reversely correlated with multiple system atrophy and Parkinson's disease

XY Li, T Xue, H Lai, J Dai, F Peng, F Xu, J Zhu, X Li… - Heliyon, 2024 - cell.com
Introduction Multiple system atrophy (MSA) is a rapidly progressing neurodegenerative
disorder. Although diverse biomarkers have been established for Parkinson's disease (PD) …

[HTML][HTML] Aberrant Metabolism of Neurovascular Unit Cells on Parkinson's Disease

NA Kolotyeva, AK Berdnikov, NA Rozanova… - Opera Medica et …, 2024 - cyberleninka.ru
The focus of this review is on the study of aberrant metabolism in brain cells in Parkinson's
disease. Parkinson's disease is the second most prevalent neurodegenerative disorder …