The landscape of cancer research and cancer care in China

Z Lu, Y Chen, D Liu, X Jiao, C Liu, Y Wang, Z Zhang… - Nature Medicine, 2023 - nature.com
The rising cancer incidence rate in China poses a substantial public health concern,
although there have been remarkable improvements in the country's cancer mortality and …

IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer

N Caronni, F La Terza, FM Vittoria, G Barbiera… - Nature, 2023 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with high resistance to
therapies. Inflammatory and immunomodulatory signals co-exist in the pancreatic tumour …

Ferroptosis: Potential opportunities for natural products in cancer therapy

A Nie, C Shen, Z Zhou, J Wang, B Sun… - Phytotherapy …, 2024 - Wiley Online Library
Cancer cells often exhibit defects in the execution of cell death, resulting in poor clinical
outcomes for patients with many cancer types. Ferroptosis is a newly discovered form of …

[HTML][HTML] Association between visceral fat area and cancer prognosis: a population-based multicenter prospective study

L Li, W Li, D Xu, H He, W Yang, H Guo, X Liu… - The American Journal of …, 2023 - Elsevier
Background Diverse indicators have been used to represent adipose tissue, while the
relationship between body adipose mass and the prognosis of patients with cancer remains …

[HTML][HTML] Artificial intelligence vs. evolving super-complex tumor intelligence: critical viewpoints

NK Sharma, SC Sarode - Frontiers in Artificial Intelligence, 2023 - frontiersin.org
Recent developments in various domains have led to a growing interest in the potential of
artificial intelligence to enhance our lives and environments. In particular, the application of …

Tumor Promoters and Opportunities for Molecular Cancer Prevention

W Hill, CE Weeden, C Swanton - Cancer Discovery, 2024 - AACR
Environmental carcinogens increase cancer incidence via both mutagenic and non-
mutagenic mechanisms. There are over 500 known or suspected carcinogens classified by …

VISTA: a novel checkpoint for cancer immunotherapy

Y Gao, Y He, Y Tang, ZS Chen, M Qu - Drug Discovery Today, 2024 - Elsevier
V-domain Ig suppressor of T cell activation (VISTA) is a recently identified member of the B7
family of immunoregulatory proteins. It is pivotal for maintaining T cell quiescence and exerts …

Stem-cell states converge in multistage cutaneous squamous cell carcinoma development

MA Taylor, E Kandyba, K Halliwill, R Delrosario… - Science, 2024 - science.org
Stem cells play a critical role in cancer development by contributing to cell heterogeneity,
lineage plasticity, and drug resistance. We created gene expression networks from …

Broccoli Consumption and Risk of Cancer: An Updated Systematic Review and Meta-Analysis of Observational Studies

E Baladia, M Moñino, E Pleguezuelos, G Russolillo… - Nutrients, 2024 - mdpi.com
Background: The scientific literature has reported an inverse association between broccoli
consumption and the risk of suffering from several types of cancer; however, the results were …

The evolution of developmental biology through conceptual and technological revolutions

P Liberali, AF Schier - Cell, 2024 - cell.com
Developmental biology—the study of the processes by which cells, tissues, and organisms
develop and change over time—has entered a new golden age. After the molecular genetics …