Background Hyperuricemia may contribute to renal injury. We do not know whether use of
treatments that lower urate reduce the progression of chronic kidney disease (CKD) and …

Importance Hearing impairment (HI) is highly prevalent in older adults and has been
associated with adverse health outcomes. However, the overall economic impact of HI is not …

Background In this randomized clinical trial, we aimed to determine whether increasing the
frequency of in-center hemodialysis would result in beneficial changes in left ventricular …

Background and objectives: Very few large-scale studies have investigated the determinants
of health-related quality of life (HRQOL) in chronic kidney disease (CKD) patients not on …

Depression is well established as a prevalent mental health problem for people with ESRD
and is associated with morbidity and mortality. However, depression in this population …

BACKGROUND: Anxiety is a complicating comorbid diagnosis in many patients with medical
illnesses. In patients with end-stage renal disease (ESRD), anxiety disorders often are …

Background: For every patient with chronic kidney disease who undergoes renal-
replacement therapy, there is one patient who undergoes conservative management of their …

BACKGROUND. To clarify the benefits of nephron‐sparing surgery among patients with
early‐stage kidney cancer, the authors compared the frequency of renal and cardiovascular …

Background Assessment of quality of life (QOL) of patients with end-stage renal disease has
become increasingly important, both in order to evaluate the influence of the disease on …

Very few biomarkers exist for monitoring chronic kidney disease (CKD). We have recently
shown that serum neutrophil gelatinase-associated lipocalin (NGAL) represents a novel …