[HTML][HTML] Exercise training maintains cardiovascular health: signaling pathways involved and potential therapeutics

H Chen, C Chen, M Spanos, G Li, R Lu, Y Bei… - … and Targeted Therapy, 2022 - nature.com
Exercise training has been widely recognized as a healthy lifestyle as well as an effective
non-drug therapeutic strategy for cardiovascular diseases (CVD). Functional and …

[HTML][HTML] Effects of different intensities and durations of aerobic exercise on vascular endothelial function in middle-aged and elderly people: a meta-analysis

Q You, L Yu, G Li, H He, Y Lv - Frontiers in Physiology, 2022 - frontiersin.org
Background Previous studies have found that aerobic exercise was more effective in
improving vascular endothelial function than resistance training, high-intensity interval …

[HTML][HTML] Selected plant-derived polyphenols as potential therapeutic agents for peripheral artery disease: Molecular mechanisms, efficacy and safety

G Froldi, E Ragazzi - Molecules, 2022 - mdpi.com
Vascular diseases, such as peripheral artery disease (PAD), are associated with diabetes
mellitus and a higher risk of cardiovascular disease and even death. Surgical …

[HTML][HTML] Is there evidence for the development of sex-specific guidelines for ultramarathon coaches and athletes? A systematic review

CPMG Kelly - Sports medicine-open, 2023 - Springer
Background There is evidence of sex differences in the physiology of endurance exercise,
yet most of the advice and guidelines on training, racing, nutrition, and recovery for …

Associations of lifelong exercise characteristics with valvular function and aortic diameters in patients with a bicuspid aortic valve

BA Schreurs, MTE Hopman, CM Bakker… - Journal of the …, 2024 - Am Heart Assoc
Background The potential impact of exercise on valvular function and aortic diameters in
patients with a bicuspid aortic valve remains unclear. Therefore, we assessed the …

Guanxin V relieves ventricular remodeling by inhibiting inflammation: implication from virtual screening, systematic pharmacology, molecular docking, and …

B Liang, X Zhang, N Gu - Chinese Journal of Integrative Medicine, 2023 - Springer
Objective To reveal the anti-inflammatory mechanism of Guanxin V, which is prescribed for
ventricular remodeling in clinical practice. Methods Guanxin V-, ventricular remodeling-, and …

[HTML][HTML] The role of estrogens and vitamin D in cardiomyocyte protection: a female perspective

C Crescioli - Biomolecules, 2021 - mdpi.com
Women experience a dramatical raise in cardiovascular events after menopause. The
decline in estrogens is pointed to as the major responsible trigger for the increased risk of …

[HTML][HTML] Maternal high-intensity interval training as a suitable approach for offspring's heart protection in rat: evidence from oxidative stress and mitochondrial genes

R Mohammadkhani, A Komaki, SA Karimi… - Frontiers in …, 2023 - frontiersin.org
Considerable scientific evidence suggests that the intrauterine environment plays a crucial
role in determining the long-term health of offspring. The present study aims to investigate …

Moderate-Intensity and High-Intensity Interval Exercise Training Offer Equal Cardioprotection, with Different Mechanisms, during the Development of Type 2 Diabetes …

S D'Haese, L Claes, I de Laat, S Van Campenhout… - Nutrients, 2024 - mdpi.com
Endurance exercise training is a promising cardioprotective strategy in type 2 diabetes
mellitus (T2DM), but the impact of its intensity is not clear. We aimed to investigate whether …

Combined cardiovascular effects of ovariectomy and high-intensity interval training in female spontaneously hypertensive rats

A Krzesiak, C Enea, JF Faivre… - Journal of Applied …, 2024 - journals.physiology.org
Hypertensive postmenopausal women are more likely to develop adverse cardiac
remodeling and respond less effectively to drug treatment than men. High-intensity interval …