Given the highly increased incidence of human diseases, a better understanding of the
related mechanisms regarding endogenous metabolism is urgently needed. Mass …

Background Based on recent research reports, dysbiosis and improper concentrations of
microbial metabolites in the gut may result into the carcinogenesis of colorectal cancer …

Tryptophan metabolism, via the kynurenine (Kyn) pathway, and microbial transformation of
tryptophan to indolic compounds are fundamental for host health; both of which are altered …

Abstract Akkermansia muciniphila (A. muciniphila), a gram-negative anaerobic bacterium, is
selectively decreased in the fecal microbiota of patients with colorectal cancer (CRC), but its …

In recent years, more and more data indicate the effect of human microbiota on
carcinogenesis. Despite the numerous studies on the relationship between gut microbiota …

Colorectal cancer (CRC) is one of the most prevalent and life-threatening cancer types with
limited therapeutic options worldwide. Gut microbiota has been recognized as the pivotal …

Multi-omic studies of the human gut microbiome are crucial for understanding its role in
disease across multiple functional layers. Nevertheless, integrating and analyzing such …

Herein, we studied the interaction of bovine pancreatic ribonuclease (RNase A) with [VIVO
(8-HQ) 2]–a promising antitrypanosomal, antituberculosis, and antitumor vanadium complex …

The concept of being able to urinate in a cup and screen for colorectal cancer (CRC) is
fascinating to the public at large. Here, a simple and label-free urine test based on surface …

Functional metabolomics could bring correlative information about specific cell types under
different conditions for exploring cell properties and functions. In this study, we adopt a non …