Role of the Exposome in Neurodegenerative Disease: Recent Insights and Future Directions
SA Sakowski, EJ Koubek, KS Chen… - Annals of …, 2024 - Wiley Online Library
Neurodegenerative diseases are increasing in prevalence and place a significant burden on
society. The causes are multifactorial and complex, and increasing evidence suggests a …
society. The causes are multifactorial and complex, and increasing evidence suggests a …
Immunological aspects of central neurodegeneration
M Niso-Santano, JM Fuentes, L Galluzzi - Cell Discovery, 2024 - nature.com
The etiology of various neurodegenerative disorders that mainly affect the central nervous
system including (but not limited to) Alzheimer's disease, Parkinson's disease and …
system including (but not limited to) Alzheimer's disease, Parkinson's disease and …
Pectolinarigenin Improves Oxidative Stress and Apoptosis in Mouse NSC-34 Motor Neuron Cell Lines Induced by C9-ALS-Associated Proline–Arginine Dipeptide …
RH Fu - Antioxidants, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is considered a fatal progressive degeneration of motor
neurons (MN) caused by oxidative stress and mitochondrial dysfunction. There are currently …
neurons (MN) caused by oxidative stress and mitochondrial dysfunction. There are currently …
Avocational exposure associations with ALS risk, survival, and phenotype: A Michigan-based case-control study
Introduction Environmental exposures strongly influence ALS risk and identification is
needed to reduce ALS burden. Participation in hobbies and exercise may alter ALS risk and …
needed to reduce ALS burden. Participation in hobbies and exercise may alter ALS risk and …
Effects of the Toxic Non-Protein Amino Acid β-Methylamino-L-Alanine (BMAA) on Intracellular Amino Acid Levels in Neuroblastoma Cells
The cyanobacterial non-protein amino acid (AA) β-Methylamino-L-alanine (BMAA) is
considered to be a neurotoxin. BMAA caused histopathological changes in brains and …
considered to be a neurotoxin. BMAA caused histopathological changes in brains and …
[HTML][HTML] Metal mixtures associate with higher amyotrophic lateral sclerosis risk and mortality independent of genetic risk and correlate to self-reported exposures: a …
Background: The pathogenesis of amyotrophic lateral sclerosis (ALS) involves both genetic
and environmental factors. This study investigates associations between metal measures in …
and environmental factors. This study investigates associations between metal measures in …
Nanoplastics and Neurodegeneration in ALS
Plastic production, which exceeds one million tons per year, is of global concern. The
constituent low-density polymers enable spread over large distances and micro/nano …
constituent low-density polymers enable spread over large distances and micro/nano …
Introducing the Role of Genotoxicity in Neurodegenerative Diseases and Neuropsychiatric Disorders
GE Kisby, PS Spencer - International Journal of Molecular Sciences, 2024 - mdpi.com
Decades of research have identified genetic and environmental factors involved in
agerelated neurodegenerative diseases and, to a lesser extent, neuropsychiatric disorders …
agerelated neurodegenerative diseases and, to a lesser extent, neuropsychiatric disorders …
Residential exposure associations with ALS risk, survival, and phenotype: a Michigan-based case-control study
Background: Environmental exposures impact amyotrophic lateral sclerosis (ALS) risk and
progression, a fatal and progressive neurodegenerative disease. Better characterization of …
progression, a fatal and progressive neurodegenerative disease. Better characterization of …
[PDF][PDF] Drug Screening and Validation Targeting TDP-43 Proteinopathy for Amyotrophic Lateral Sclerosis
J Xin, S Huang, J Wen, Y Li, A Li… - Aging and …, 2024 - researchgate.net
Amyotrophic lateral sclerosis (ALS) stands as a rare, yet severely debilitating disorder
marked by the deterioration of motor neurons (MNs) within the brain and spinal cord, which …
marked by the deterioration of motor neurons (MNs) within the brain and spinal cord, which …