Auranofin (AUR) is an orally available lipophilic gold-based anti-inflammatory compound
used for the treatment of rheumatoid arthritis (RA). Recent evidence indicates that AUR may …

Viral infections remain a major cause of economic loss with an unmet need for novel
therapeutic agents. Ivermectin is a putative antiviral compound; the proposed mechanism is …

Ae. aegypti mosquitoes transmit some of the most important human viral diseases that are
responsible for a significant public health burden worldwide. The small interfering RNA …

Biorational insecticides (for instance, avermectins, spinosins, azadirachtin, and
afidopyropen) of natural origin are increasingly being used in agriculture. The review …

Chikungunya virus (CHIKV) is the causative agent of chikungunya fever (CHIKF) and is
categorized as a (n)(re) emerging arbovirus. CHIKV has repeatedly been responsible for …

Cholesterol plays critical functions in arranging the biophysical attributes of proteins and
lipids in the plasma membrane. For various viruses, an association with cholesterol for virus …

Japanese encephalitis virus (JEV), a major cause of Japanese encephalitisis, is an
arbovirus that belongs to the genus Flavivirus of the family Flaviviridae. Currently, there is no …

Flaviviruses have posed a serious threat to human health in the past decades, and effective
therapeutic drugs are lacking; thus, treatment of flavivirus infection is a great challenge. The …

Bunyaviruses are significant human pathogens, causing diseases ranging from hemorrhagic
fevers to encephalitis. Among these viruses, La Crosse virus (LACV), a member of the …

Insect odorant-binding proteins (OBPs) are small soluble proteins that have been assigned
roles in olfaction, but their other potential functions have not been extensively explored …