Antioxidant activities of quercetin and its complexes for medicinal application

D Xu, MJ Hu, YQ Wang, YL Cui - Molecules, 2019 - mdpi.com
Quercetin is a bioactive compound that is widely used in botanical medicine and traditional
Chinese medicine due to its potent antioxidant activity. In recent years, antioxidant activities …

Anti-inflammatory effects of flavonoids in neurodegenerative disorders

C Spagnuolo, S Moccia, GL Russo - European journal of medicinal …, 2018 - Elsevier
Neuroinflammation is one of the main mechanisms involved in the progression of several
neurodegenerative diseases, such as Parkinson, Alzheimer, multiple sclerosis, amyotrophic …

Prefrontal excitatory/inhibitory balance in stress and emotional disorders: evidence for over-inhibition

CE Page, L Coutellier - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
Chronic stress-induced emotional disorders like anxiety and depression involve imbalances
between the excitatory glutamatergic system and the inhibitory GABAergic system in the …

[HTML][HTML] Targeting neuroinflammation by polyphenols: A promising therapeutic approach against inflammation-associated depression

MA Tayab, MN Islam, KAA Chowdhury… - Biomedicine & …, 2022 - Elsevier
Depression is the most prevalent and debilitating mental disorder that affects a substantial
number of people globally, hindering all aspects of their lives and leading to a high number …

Antidepressant Potential of Quercetin and its Glycoside Derivatives: A Comprehensive Review and Update

S Chen, Y Tang, Y Gao, K Nie, H Wang, H Su… - Frontiers in …, 2022 - frontiersin.org
Depression is a global health problem with growing prevalence rates and serious impacts
on the daily life of patients. However, the side effects of currently used antidepressants …

Re-evaluation of the interrelationships among the behavioral tests in rats exposed to chronic unpredictable mild stress

C Hu, Y Luo, H Wang, S Kuang, G Liang, Y Yang… - PloS one, 2017 - journals.plos.org
The chronic unpredictable mild stress model of depression has been widely used as an
experimental tool to investigate human psychopathology. Our objective was to provide an …

The roles of flavonols/flavonoids in neurodegeneration and neuroinflammation

Z Calis, R Mogulkoc, AK Baltaci - Mini Reviews in Medicinal …, 2020 - ingentaconnect.com
The inflammatory process in the human body is a physiological response involving many
cellular types and mediators. It results in scar formation to separate the damaged area from …

Anti-inflammatory, antioxidant, and neuroprotective effects of polyphenols—polyphenols as an element of diet therapy in depressive disorders

A Winiarska-Mieczan, M Kwiecień… - International Journal of …, 2023 - mdpi.com
Depressive disorders can affect up to 350 million people worldwide, and in developed
countries, the percentage of patients with depressive disorders may be as high as 10 …

Quercetin alleviates chronic unpredictable mild stress-induced depressive-like behaviors by promoting adult hippocampal neurogenesis via FoxG1/CREB/BDNF …

ZX Ma, RY Zhang, WJ Rui, ZQ Wang, X Feng - Behavioural brain research, 2021 - Elsevier
Quercetin, a naturally occurring flavonoid, has been reported to exert antidepressant effects,
however, the underlying mechanisms are still uncertain. Recent studies have demonstrated …

Quercetin in food: possible mechanisms of its effect on memory

F Babaei, M Mirzababaei… - Journal of food …, 2018 - Wiley Online Library
Abstract Quercetin (3, 3′, 4′, 5, 7‐pentahydroxyflavone) is found in vegetables and fruits.
It is one of the major flavonoids that is part of human diets. Quercetin has several …