Breaking the boundaries of interacting with the human brain using adaptive closed-loop stimulation
The human brain is arguably one of the most complex systems in nature. To understand how
it operates, it is essential to understand the link between neural activity and behavior …
it operates, it is essential to understand the link between neural activity and behavior …
Metastable dynamics of neural circuits and networks
BAW Brinkman, H Yan, A Maffei, IM Park… - Applied Physics …, 2022 - pubs.aip.org
Cortical neurons emit seemingly erratic trains of action potentials or “spikes,” and neural
network dynamics emerge from the coordinated spiking activity within neural circuits. These …
network dynamics emerge from the coordinated spiking activity within neural circuits. These …
[HTML][HTML] Deep brain stimulation for depression informed by intracranial recordings
The success of deep brain stimulation (DBS) for treating Parkinson's disease has led to its
application to several other disorders, including treatment-resistant depression. Results with …
application to several other disorders, including treatment-resistant depression. Results with …
Electron conductive and transparent hydrogels for recording brain neural signals and neuromodulation
Recording brain neural signals and optogenetic neuromodulations open frontiers in
decoding brain neural information and neurodegenerative disease therapeutics …
decoding brain neural information and neurodegenerative disease therapeutics …
Activity-dependent recruitment of inhibition and excitation in the awake mammalian cortex during electrical stimulation
Electrical stimulation is an effective tool for mapping and altering brain connectivity, with
applications ranging from treating pharmacology-resistant neurological disorders to …
applications ranging from treating pharmacology-resistant neurological disorders to …
Dynamical flexible inference of nonlinear latent factors and structures in neural population activity
Modelling the spatiotemporal dynamics in the activity of neural populations while also
enabling their flexible inference is hindered by the complexity and noisiness of neural …
enabling their flexible inference is hindered by the complexity and noisiness of neural …
Multiscale low-dimensional motor cortical state dynamics predict naturalistic reach-and-grasp behavior
H Abbaspourazad, M Choudhury, YT Wong… - Nature …, 2021 - nature.com
Motor function depends on neural dynamics spanning multiple spatiotemporal scales of
population activity, from spiking of neurons to larger-scale local field potentials (LFP). How …
population activity, from spiking of neurons to larger-scale local field potentials (LFP). How …
Autonomous optimization of neuroprosthetic stimulation parameters that drive the motor cortex and spinal cord outputs in rats and monkeys
Neural stimulation can alleviate paralysis and sensory deficits. Novel high-density neural
interfaces can enable refined and multipronged neurostimulation interventions. To achieve …
interfaces can enable refined and multipronged neurostimulation interventions. To achieve …
Local and distant cortical responses to single pulse intracranial stimulation in the human brain are differentially modulated by specific stimulation parameters
Background Electrical neuromodulation via direct electrical stimulation (DES) is an
increasingly common therapy for a wide variety of neuropsychiatric diseases. Unfortunately …
increasingly common therapy for a wide variety of neuropsychiatric diseases. Unfortunately …
Modeling and dissociation of intrinsic and input-driven neural population dynamics underlying behavior
Neural dynamics can reflect intrinsic dynamics or dynamic inputs, such as sensory inputs or
inputs from other brain regions. To avoid misinterpreting temporally structured inputs as …
inputs from other brain regions. To avoid misinterpreting temporally structured inputs as …