Changes in lipids composition and metabolism in colorectal cancer: a review

A Pakiet, J Kobiela, P Stepnowski, T Sledzinski… - Lipids in health and …, 2019 - Springer
Altered metabolism of lipids is currently considered a hallmark characteristic of many
malignancies, including colorectal cancer (CRC). Lipids are a large group of metabolites …

A conjunctive lipidomic approach reveals plasma ethanolamine plasmalogens and fatty acids as early diagnostic biomarkers for colorectal cancer patients

T Liu, Z Tan, J Yu, F Peng, J Guo, W Meng… - Expert review of …, 2020 - Taylor & Francis
Background: Colorectal cancer (CRC) represents a third leading cause of cancer-related
death worldwide. The reliable diagnostic biomarkers for detecting CRC at early stage is …

[HTML][HTML] Metabolomics and transcriptomics identify pathway differences between visceral and subcutaneous adipose tissue in colorectal cancer patients: the ColoCare …

DB Liesenfeld, D Grapov, JF Fahrmann, M Salou… - The American journal of …, 2015 - Elsevier
Background: Metabolic and transcriptomic differences between visceral adipose tissue
(VAT) and subcutaneous adipose tissue (SAT) compartments, particularly in the context of …

ω3 Polyunsaturated fatty acids as immunomodulators in colorectal cancer: new potential role in adjuvant therapies

S Miccadei, R Masella, AM Mileo… - Frontiers in …, 2016 - frontiersin.org
Diet composition may affect the onset and progression of chronic degenerative diseases,
including cancer, whose pathogenesis relies on inflammatory processes. Growing evidence …

[HTML][HTML] Fatty acid composition of adipose tissue and colorectal cancer: a case-control study

V Cottet, C Vaysse, ML Scherrer… - The American journal of …, 2015 - Elsevier
Background: Unlike experimental results, epidemiologic studies that used dietary
questionnaires were not convincing as regards the relations between dietary fatty acids …

Dietary trans fatty acids and risk of colorectal cancer: a systematic review and meta-analysis of observational studies

F Salemi, S Beigrezaei, V Arabi… - European Journal of …, 2023 - Springer
Purpose Although trans fatty acid has been associated with diabetes and cardiovascular
disorders, studies gave conflicting results when examined their impact on colorectal cancer …

Dietary fatty acids at the crossroad between obesity and colorectal cancer: fine regulators of adipose tissue homeostasis and immune response

M Del Cornò, R Varì, B Scazzocchio, B Varano… - Cells, 2021 - mdpi.com
Colorectal cancer (CRC) is among the major threatening diseases worldwide, being the
third most common cancer, and a leading cause of death, with a global incidence expected …

Key markers involved in the anticolon cancer response of CD8+ T cells through the regulation of cholesterol metabolism

L Dong, X Yang, Y Wang, Y Jin, Q Zhou… - Journal of …, 2021 - Wiley Online Library
Background. T cell‐mediated antitumor immune response is the basis of colorectal cancer
(CRC) immunotherapy. Cholesterol plays an important role in T cell signal transduction and …

Systematic investigation of genetically determined plasma and urinary metabolites to discover potential interventional targets for colorectal cancer

J Sun, J Zhao, S Zhou, X Li, T Li, L Wang… - JNCI: Journal of the …, 2024 - academic.oup.com
Background We aimed to identify plasma and urinary metabolites related to colorectal
cancer (CRC) risk and elucidate their mediator role in the associations between modifiable …

Biospecimen long-chain N-3 PUFA and risk of colorectal cancer: a meta-analysis of data from 60,627 individuals

B Yang, FL Wang, XL Ren, D Li - PLoS One, 2014 - journals.plos.org
Background Several prospective cohort and case-control studies reported the inconsistent
association between biospecimen composition of C20 and C22 long-chain (LC) n-3 …