Interleukin-17A and keratinocytes in psoriasis

M Furue, K Furue, G Tsuji, T Nakahara - International journal of molecular …, 2020 - mdpi.com
The excellent clinical efficacy of anti-interleukin 17A (IL-17A) biologics on psoriasis indicates
a crucial pathogenic role of IL-17A in this autoinflammatory skin disease. IL-17A accelerates …

[HTML][HTML] Thymic stromal lymphopoietin isoforms, inflammatory disorders, and cancer

G Varricchi, A Pecoraro, G Marone… - Frontiers in …, 2018 - frontiersin.org
Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine originally isolated from a
murine thymic stromal cell line. TSLP exerts its biological effects by binding to a high-affinity …

Comorbidities associated with psoriatic arthritis: review and update

LM Perez-Chada, JF Merola - Clinical Immunology, 2020 - Elsevier
Psoriatic arthritis is an inflammatory arthropathy frequently associated with psoriasis and
several other comorbidities. The goal of this review is to summarize the available evidence …

Psoriasis and metabolic syndrome: implications for the management and treatment of psoriasis

JJ Wu, A Kavanaugh, MG Lebwohl… - Journal of the …, 2022 - Wiley Online Library
Psoriasis is a chronic systemic inflammatory disorder associated with several comorbidities
in addition to the characteristic skin lesions. Metabolic syndrome (MetS) is the most frequent …

Berberine: a review of its pharmacokinetics properties and therapeutic potentials in diverse vascular diseases

X Ai, P Yu, L Peng, L Luo, J Liu, S Li, X Lai… - Frontiers in …, 2021 - frontiersin.org
Traditional Chinese medicine plays a significant role in the treatment of various diseases
and has attracted increasing attention for clinical applications. Vascular diseases affecting …

Exploring the Pathogenesis of Psoriasis Complicated With Atherosclerosis via Microarray Data Analysis

W Su, Y Zhao, Y Wei, X Zhang, J Ji, S Yang - Frontiers in immunology, 2021 - frontiersin.org
Background Although more and more evidence has supported psoriasis is prone to
atherosclerosis, the common mechanism of its occurrence is still not fully elucidated. The …

[HTML][HTML] Pathogenesis of chronic plaque psoriasis and its intersection with cardio-metabolic comorbidities

P Gisondi, F Bellinato, G Girolomoni… - Frontiers in …, 2020 - frontiersin.org
Psoriasis is a chronic, systemic immune-mediated disease characterized by development of
erythematous, indurated, scaly, pruritic plaques on the skin. Psoriasis is frequently …

The role of Th17 cells in psoriasis

B Li, L Huang, P Lv, X Li, G Liu, Y Chen, Z Wang… - Immunologic …, 2020 - Springer
Abstract T helper 17 (Th17) cells have been involved in the pathogenesis of many
autoimmune and inflammatory diseases, like psoriasis, multiple sclerosis (MS), rheumatoid …

Biologic and small-molecule therapies for moderate-to-severe psoriasis: focus on psoriasis comorbidities

Y Jiang, Y Chen, Q Yu, Y Shi - BioDrugs, 2023 - Springer
Psoriasis is a systemic immune-mediated disease associated with an increased risk of
comorbidities, such as psoriatic arthritis, cardiovascular disease, metabolic syndrome …

Biologics for the primary care physician: Review and treatment of psoriasis

ED Schadler, B Ortel, SL Mehlis - Disease-a-Month, 2019 - Elsevier
Psoriasis is a chronic inflammatory disease that affects approximately 7.5 million people in
the United States. The disease results in significant suffering, morbidity, and economic …