[HTML][HTML] A systematic review of computational approaches to understand cancer biology for informed drug repurposing

F Ahmed, A Samantasinghar, AM Soomro, S Kim… - Journal of Biomedical …, 2023 - Elsevier
Cancer is the second leading cause of death globally, trailing only heart disease. In the
United States alone, 1.9 million new cancer cases and 609,360 deaths were recorded for …

Glycan-specific molecularly imprinted polymers towards cancer diagnostics: merits, applications, and future perspectives

P Li, Z Liu - Chemical Society Reviews, 2024 - pubs.rsc.org
Aberrant glycans are a hallmark of cancer states. Notably, emerging evidence has
demonstrated that the diagnosis of cancers with tumour-specific glycan patterns holds great …

[HTML][HTML] Preclinical modeling in depression and anxiety: Current challenges and future research directions

M Tanaka, Á Szabó, L Vécsei - Advances in Clinical and …, 2023 - advances.umw.edu.pl
This editorial highlights the limitations of preclinical models in accurately reflecting the
complexity of anxiety and depression, which leads to a lack of effective treatments for these …

miRNA dysregulation is an emerging modulator of genomic instability

APF Cardoso, M Banerjee, AN Nail, A Lykoudi… - Seminars in cancer …, 2021 - Elsevier
Genomic instability consists of a range of genetic alterations within the genome that
contributes to tumor heterogeneity and drug resistance. It is a well-established characteristic …

[HTML][HTML] Toxicity by descent: A comparative approach for chemical hazard assessment

JK Colbourne, JR Shaw, E Sostare, C Rivetti… - Environmental …, 2022 - Elsevier
Toxicology is traditionally divided between human and eco-toxicology. In the shared pursuit
of environmental health, this separation does not account for discoveries made in the …

[HTML][HTML] Exploring the biological activity and mechanism of xenoestrogens and phytoestrogens in cancers: emerging methods and concepts

X Wang, D Ha, R Yoshitake, YS Chan… - International journal of …, 2021 - mdpi.com
Xenoestrogens and phytoestrogens are referred to as “foreign estrogens” that are produced
outside of the human body and have been shown to exert estrogen-like activity …

[HTML][HTML] Tumor vasculature vs tumor cell targeting: Understanding the latest trends in using functional nanoparticles for cancer treatment

NS Awad, NM Salkho, WH Abuwatfa, V Paul… - OpenNano, 2023 - Elsevier
Delivering drugs to tumors using nanoparticles (NPs) has shown promising potential in
promoting targeted drug delivery of antineoplastic agents to enhance their efficiency while …

Instigation of the epoch of nanovaccines in cancer immunotherapy

S Shah, P Famta, V Tiwari, AK Kotha… - Wiley …, 2023 - Wiley Online Library
Cancer is an unprecedented proliferation of cells leading to abnormalities in differentiation
and maturation. Treatment of primary and metastatic cancer is challenging. In addition to …

Long-term exposure to fine particulate matter and site-specific cancer mortality: A difference-in-differences analysis in Jiangsu province, China

Z Fan, Y Li, J Wei, G Chen, R Wang, R Xu, T Liu… - Environmental …, 2023 - Elsevier
Background Accumulating studies have reported that chronic exposure to ambient fine
particulate matter (PM 2.5) can lead to adverse effects on lung cancer mortality; however …

[HTML][HTML] Targeting homocysteine and hydrogen sulfide balance as future therapeutics in cancer treatment

A Majumder - Antioxidants, 2023 - mdpi.com
A high level of homocysteine (Hcy) is associated with oxidative/ER stress, apoptosis, and
impairment of angiogenesis, whereas hydrogen sulfide (H2S) has been found to reverse this …