[HTML][HTML] A systematic review of computational approaches to understand cancer biology for informed drug repurposing
Cancer is the second leading cause of death globally, trailing only heart disease. In the
United States alone, 1.9 million new cancer cases and 609,360 deaths were recorded for …
United States alone, 1.9 million new cancer cases and 609,360 deaths were recorded for …
Glycan-specific molecularly imprinted polymers towards cancer diagnostics: merits, applications, and future perspectives
P Li, Z Liu - Chemical Society Reviews, 2024 - pubs.rsc.org
Aberrant glycans are a hallmark of cancer states. Notably, emerging evidence has
demonstrated that the diagnosis of cancers with tumour-specific glycan patterns holds great …
demonstrated that the diagnosis of cancers with tumour-specific glycan patterns holds great …
[HTML][HTML] Preclinical modeling in depression and anxiety: Current challenges and future research directions
This editorial highlights the limitations of preclinical models in accurately reflecting the
complexity of anxiety and depression, which leads to a lack of effective treatments for these …
complexity of anxiety and depression, which leads to a lack of effective treatments for these …
miRNA dysregulation is an emerging modulator of genomic instability
Genomic instability consists of a range of genetic alterations within the genome that
contributes to tumor heterogeneity and drug resistance. It is a well-established characteristic …
contributes to tumor heterogeneity and drug resistance. It is a well-established characteristic …
[HTML][HTML] Toxicity by descent: A comparative approach for chemical hazard assessment
JK Colbourne, JR Shaw, E Sostare, C Rivetti… - Environmental …, 2022 - Elsevier
Toxicology is traditionally divided between human and eco-toxicology. In the shared pursuit
of environmental health, this separation does not account for discoveries made in the …
of environmental health, this separation does not account for discoveries made in the …
[HTML][HTML] Exploring the biological activity and mechanism of xenoestrogens and phytoestrogens in cancers: emerging methods and concepts
X Wang, D Ha, R Yoshitake, YS Chan… - International journal of …, 2021 - mdpi.com
Xenoestrogens and phytoestrogens are referred to as “foreign estrogens” that are produced
outside of the human body and have been shown to exert estrogen-like activity …
outside of the human body and have been shown to exert estrogen-like activity …
[HTML][HTML] Tumor vasculature vs tumor cell targeting: Understanding the latest trends in using functional nanoparticles for cancer treatment
Delivering drugs to tumors using nanoparticles (NPs) has shown promising potential in
promoting targeted drug delivery of antineoplastic agents to enhance their efficiency while …
promoting targeted drug delivery of antineoplastic agents to enhance their efficiency while …
Instigation of the epoch of nanovaccines in cancer immunotherapy
Cancer is an unprecedented proliferation of cells leading to abnormalities in differentiation
and maturation. Treatment of primary and metastatic cancer is challenging. In addition to …
and maturation. Treatment of primary and metastatic cancer is challenging. In addition to …
Long-term exposure to fine particulate matter and site-specific cancer mortality: A difference-in-differences analysis in Jiangsu province, China
Background Accumulating studies have reported that chronic exposure to ambient fine
particulate matter (PM 2.5) can lead to adverse effects on lung cancer mortality; however …
particulate matter (PM 2.5) can lead to adverse effects on lung cancer mortality; however …
[HTML][HTML] Targeting homocysteine and hydrogen sulfide balance as future therapeutics in cancer treatment
A Majumder - Antioxidants, 2023 - mdpi.com
A high level of homocysteine (Hcy) is associated with oxidative/ER stress, apoptosis, and
impairment of angiogenesis, whereas hydrogen sulfide (H2S) has been found to reverse this …
impairment of angiogenesis, whereas hydrogen sulfide (H2S) has been found to reverse this …