Antiviral peptides as promising therapeutic drugs

LCP Vilas Boas, ML Campos, RLA Berlanda… - Cellular and Molecular …, 2019 - Springer
While scientific advances have led to large-scale production and widespread distribution of
vaccines and antiviral drugs, viruses still remain a major cause of human diseases today …

Second-line HIV treatment failure in sub-Saharan Africa: A systematic review and meta-analysis

D Edessa, M Sisay, F Asefa - PloS one, 2019 - journals.plos.org
Background Increased second-line antiretroviral therapy (ART) failure rate narrows future
options for HIV/AIDS treatment. It has critical implications in resource-limited settings; …

Meta-iAVP: a sequence-based meta-predictor for improving the prediction of antiviral peptides using effective feature representation

N Schaduangrat, C Nantasenamat… - International journal of …, 2019 - mdpi.com
In spite of the large-scale production and widespread distribution of vaccines and antiviral
drugs, viruses remain a prominent human disease. Recently, the discovery of antiviral …

[HTML][HTML] Routine versus clinically driven laboratory monitoring and first-line antiretroviral therapy strategies in African children with HIV (ARROW): a 5-year open-label …

ARROW Trial Team - The Lancet, 2013 - Elsevier
BACKGROUND: No trials have investigated routine laboratory monitoring for children with
HIV, nor four-drug induction strategies to increase durability of first-line antiretroviral therapy …

The need for second-line antiretroviral therapy in adults in sub-Saharan Africa up to 2030: a mathematical modelling study

J Estill, N Ford, L Salazar-Vizcaya, AD Haas… - The Lancet …, 2016 - thelancet.com
Background The number of patients in need of second-line antiretroviral drugs is increasing
in sub-Saharan Africa. We aimed to project the need of second-line antiretroviral therapy in …

Examining the relationship between psychological distress and adherence to anti-retroviral therapy among Ugandan adolescents living with HIV

M Mutumba, V Musiime, JM Lepkwoski, GW Harper… - AIDS care, 2016 - Taylor & Francis
Psychological distress is common among adolescents living with HIV (ALHIV) worldwide,
and has been associated with non-adherence to anti-retroviral therapy (ART), leading to …

Rate of virological failure and HIV-1 drug resistance among HIV-infected adolescents in routine follow-up on health facilities in Cameroon

CI Penda, M Moukoko Mbonjo, J Fokam, ABD Djeuda… - PLoS …, 2022 - journals.plos.org
The objective of this study was to determine the rates of virological failure (VF) and HIV drug
resistance (HIVDR) amongst adolescents on antiretroviral Therapy (ART). A retrospectively …

Drug resistance in the HIV-1-infected paediatric population worldwide: a systematic review

P Rojas Sánchez, A Holguín - Journal of Antimicrobial …, 2014 - academic.oup.com
Background Drug resistance monitoring of the paediatric HIV-1-infected population is
required to optimize treatment success and preserve future treatment options. Objectives To …

Antiviral peptides as anti-influenza agents

M Agamennone, M Fantacuzzi, G Vivenzio… - International Journal of …, 2022 - mdpi.com
Influenza viruses represent a leading cause of high morbidity and mortality worldwide.
Approaches for fighting flu are seasonal vaccines and some antiviral drugs. The …

Development of antiretroviral resistance in children with HIV in low-and middle-income countries

F Fitzgerald, M Penazzato, D Gibb - The Journal of infectious …, 2013 - academic.oup.com
With antiretroviral therapy (ART) recommended by the World Health Organization (WHO) for
children aged< 2 years with human immunodeficiency virus (HIV) and continuing global …