Background The Danish National Patient Registry (DNPR) is one of the world's oldest
nationwide hospital registries and is used extensively for research. Many studies have …

Background: Interoception and heart rate variability have been found to predict outcomes of
mental health and well-being. However, these have usually been investigated …

Background and Aims Electronic health record (EHR)‐based research allows the capture of
large amounts of data, which is necessary in NAFLD, where the risk of clinical liver …

Importance Prosthetic mesh is frequently used to reinforce the repair of abdominal wall
incisional hernias. The benefits of mesh for reducing the risk of hernia recurrence or the long …

Background Adhering to weight loss interventions is difficult for many people. The majority of
those who are overweight or obese and attempt to lose weight are simply not successful …

Cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapies target the
underlying cause of cystic fibrosis (CF), and are generally well-tolerated; however, real …

Bias analysis quantifies the infiuence of systematic error on an epidemiology study's
estimate of occurrence or estimate of association. The fundamental methods of bias analysis …

Importance Intensive follow-up of patients after curative surgery for colorectal cancer is
common in clinical practice, but evidence of a survival benefit is limited. Objective To …

We revisited the three interrelated epidemiological concepts of effect modification,
interaction and mediation for clinical investigators and examined their applicability when …

Randomized controlled trials (RCTs) are considered the gold standard for clinical research,
thus having a high impact on clinical guidelines and our daily patients' care. However …