Ferroptosis is a form of regulatory cell death distinct from caspase-dependent apoptosis and
plays an important role in life entities. Since ferroptosis involves a variety of complex …

The research field of ferroptosis has seen exponential growth over the past few years, since
the term was coined in 2012. This unique modality of cell death, driven by iron-dependent …

Cancer metabolism is rewired to support cell survival in response to intrinsic and
environmental stressors. Identification of strategies to target these adaptions is an area of …

The COVID-19 pandemic caused by the coronavirus (SARS-CoV-2) has taken the world by
surprise into a major crisis of overwhelming morbidity and mortality. This highly infectious …

Ferroptosis is a unique type of non-apoptotic cell death resulting from the unrestrained
occurrence of peroxidized phospholipids, which are subject to iron-mediated production of …

Macroautophagy (hereafter referred to as autophagy) involves an intracellular degradation
and recycling system that, in a context-dependent manner, can either promote cell survival …

Pancreatic cancer tends to be highly resistant to current therapy and remains one of the
great challenges in biomedicine with very low 5-year survival rates. Here, we report that …

The term ferroptosis was coined in 2012 to describe an iron-dependent regulated form of
cell death caused by the accumulation of lipid-based reactive oxygen species; this type of …

Iron is a critical element for living cells in terrestrial life. Although iron metabolism is strictly
controlled in the body, disturbance of iron homeostasis under certain type of condition leads …

Vitamin C has been known for decades. It is common in everyday use as an element of the
diet, supplementation, and a preservative. For years, research has been conducted to …