[HTML][HTML] Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics
V Bourganis, O Kammona, A Alexopoulos… - European Journal of …, 2018 - Elsevier
Central nervous system (CNS) disorders (eg, multiple sclerosis, Alzheimer's disease, etc.)
represent a growing public health issue, primarily due to the increased life expectancy and …
represent a growing public health issue, primarily due to the increased life expectancy and …
[HTML][HTML] Intranasal nanoemulsions for direct nose-to-brain delivery of actives for CNS disorders
The treatment of various central nervous system (CNS) diseases has been challenging,
despite the rapid development of several novel treatment approaches. The blood–brain …
despite the rapid development of several novel treatment approaches. The blood–brain …
Study on the coal dust deposition fraction and site in the upper respiratory tract under different particle sizes and labor intensities
Y Cheng, H Yu, S Xie, J Zhao, Y Ye - Science of The Total Environment, 2023 - Elsevier
In order to study the dust exposure amount and coal dust deposition rule of coal miners
under different labor intensity in coal mine environment, an airflow-particle two-phase …
under different labor intensity in coal mine environment, an airflow-particle two-phase …
Airflow and particle transport in the human respiratory system
C Kleinstreuer, Z Zhang - Annual review of fluid mechanics, 2010 - annualreviews.org
Airflows in the nasal cavities and oral airways are rather complex, possibly featuring a
transition to turbulent jet-like flow, recirculating flow, Dean's flow, vortical flows, large …
transition to turbulent jet-like flow, recirculating flow, Dean's flow, vortical flows, large …
[图书][B] Multiphase flow handbook
E Michaelides, CT Crowe, JD Schwarzkopf - 2016 - books.google.com
The Multiphase Flow Handbook, Second Edition is a thoroughly updated and reorganized
revision of the late Clayton Crowe's work, and provides a detailed look at the basic concepts …
revision of the late Clayton Crowe's work, and provides a detailed look at the basic concepts …
[HTML][HTML] A review of respiratory anatomical development, air flow characterization and particle deposition
The understanding of complex inhalation and transport processes of pollutant particles
through the human respiratory system is important for investigations into dosimetry and …
through the human respiratory system is important for investigations into dosimetry and …
In silico models of aerosol delivery to the respiratory tract—development and applications
PW Longest, LT Holbrook - Advanced drug delivery reviews, 2012 - Elsevier
This review discusses the application of computational models to simulate the transport and
deposition of inhaled pharmaceutical aerosols from the site of particle or droplet formation to …
deposition of inhaled pharmaceutical aerosols from the site of particle or droplet formation to …
Study on the transport and deposition of micron-sized particles with different densities in the coal mine environment in miners
Y Cheng, H Yu, Y Ye, Y Xie, J Zhao, S Xie - Fuel, 2024 - Elsevier
To address the health problems caused by the long-term intrusion of high-concentration dust
generated in coal mining operations into the human respiratory tract, this study …
generated in coal mining operations into the human respiratory tract, this study …
Innovative preclinical models for pulmonary drug delivery research
Introduction: Pulmonary drug delivery is a complex field of research combining physics
which drive aerosol transport and deposition and biology which underpins efficacy and …
which drive aerosol transport and deposition and biology which underpins efficacy and …
Numerical predictions of submicrometer aerosol deposition in the nasal cavity using a novel drift flux approach
J Xi, PW Longest - International Journal of Heat and Mass Transfer, 2008 - Elsevier
Evaluating the health effects of inhaled submicrometer aerosols, such as combustion
particulate matter and bioaerosols, requires a thorough understanding of transport and …
particulate matter and bioaerosols, requires a thorough understanding of transport and …