Nanotherapeutics for pulmonary drug delivery: An emerging approach to overcome respiratory diseases

E Kole, K Jadhav, N Shirsath, P Dudhe… - Journal of Drug Delivery …, 2023 - Elsevier
Pulmonary diseases pose an immense threat to global health. Several nanotherapeutics-
based approaches aimed to tackle pulmonary ailments in recent years. The current …

Assessment of septal deviation effects on nasal air flow: a computational fluid dynamics model

XB Chen, HP Lee, VF Hin Chong… - The …, 2009 - Wiley Online Library
Abstract Objectives/Hypothesis: The purpose of this article is to analyze the effects of septal
deviation on the aerodynamic air flow pattern compared with that of a normal nose by …

Effects of surface smoothness on inertial particle deposition in human nasal models

JD Schroeter, GJM Garcia, JS Kimbell - Journal of aerosol science, 2011 - Elsevier
Computational fluid dynamics (CFD) predictions of inertial particle deposition have not
compared well with data from nasal replicas due to effects of surface texture and the …

[HTML][HTML] Aerosol transport modeling: the key link between lung infections of individuals and populations

C Darquenne, AAT Borojeni, MJ Colebank… - Frontiers in …, 2022 - frontiersin.org
The recent COVID-19 pandemic has propelled the field of aerosol science to the forefront,
particularly the central role of virus-laden respiratory droplets and aerosols. The pandemic …

Patient specific CFD models of nasal airflow: overview of methods and challenges

SK Kim, Y Na, JI Kim, SK Chung - Journal of biomechanics, 2013 - Elsevier
Respiratory physiology and pathology are strongly dependent on the airflow inside the nasal
cavity. However, the nasal anatomy, which is characterized by complex airway channels and …

Numerical and experimental study on the spray characteristics of full-cone pressure swirl atomizers

Y Sun, AM Alkhedhair, Z Guan, K Hooman - Energy, 2018 - Elsevier
Numerical and experimental studies have been performed to investigate the macroscopic
spray structure and spray characteristics of sprays generated by a full-cone pressure swirl …

[PDF][PDF] A review of the implications of computational fluid dynamic studies on nasal airflow and physiology

SC Leong, XB Chen, HP Lee, DY Wang - Rhinology, 2010 - researchgate.net
Background: Computational fluid dynamics has been adapted to studying nasal
aerodynamics. Aim: To review current literature on CFD studies, with an emphasis on …

Influence of mesh density on airflow and particle deposition in sinonasal airway modeling

DO Frank-Ito, M Wofford, JD Schroeter… - Journal of aerosol …, 2016 - liebertpub.com
Background: There are methodological ambiguities in the literature on mesh refinement
analysis for computational fluid dynamics (CFD) modeling of physiologically realistic airflow …

Creation of a standardized geometry of the human nasal cavity

Y Liu, MR Johnson, EA Matida… - Journal of applied …, 2009 - journals.physiology.org
A novel, standardized geometry of the human nasal cavity was created by aligning and
processing 30 sets of computed tomography (CT) scans of nasal airways of healthy subjects …

CFD–DEM simulation of particle transport and deposition in pulmonary airway

X Chen, W Zhong, X Zhou, B Jin, B Sun - Powder technology, 2012 - Elsevier
Including the effects of particle–particle collision and particle rotation as well as the volume
of particle occupied in the fluid, the Computational Fluid Dynamics (CFD)–Discrete Element …