As a human grows from birth to adulthood, both airway anatomy and breathing conditions
vary, altering the deposition rate and pattern of inhaled aerosols. However, deposition …

This study investigated the effect of modifying the design of the Cyclohaler on its
aerosolization performance and comparability to the HandiHaler at multiple flow rates. The …

Differences in nasal anatomy among human subjects may cause significant differences in
respiratory airflow patterns and subsequent dosimetry of inhaled gases and particles in the …

Several case clusters occurred in high-rise residential buildings in Hong Kong in the 2003
SARS (the severe acute respiratory syndrome) epidemic, which motivated a series of …

Background: Knowledge of the regional deposition of inhaled particles in the nose is
important for drug delivery and assessment of the toxicity of inhaled materials. In this study …

In vitro measurements of particle filtration were made for nasal geometries of 11 infants aged
3–18 months. The geometries were obtained from computed tomography (CT) scans of …

Background: Turbinate reduction surgery may be indicated for inferior turbinate enlargement
when conservative treatment fails. The aim of this study was to evaluate the effects of inferior …

Direct nose-to-brain drug delivery has multiple advantages over conventional intravenous
deliveries. However, demonstration of its clinical feasibility is still in adolescence due to the …

Turbulent flow field and particle deposition in a realistic model of human upper airway
system including: nasal cavity, nasopharynx, oropharynx, larynx and trachea were analyzed …

Indoor air quality and its effect on respiratory health are reliant on understanding the level of
inhalation exposure, particle inhalability, and particle deposition in the respiratory airway. In …