[HTML][HTML] Therapeutic promise of carotenoids as antioxidants and anti-inflammatory agents in neurodegenerative disorders

MT Kabir, MH Rahman, M Shah, MR Jamiruddin… - Biomedicine & …, 2022 - Elsevier
Abstract Neurodegenerative disorders (NDs) including Alzheimer's disease, Parkinson's
disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis have …

[HTML][HTML] Overview of oxidative stress findings in hepatic encephalopathy: from cellular and ammonium-based animal models to human data

D Simicic, C Cudalbu, K Pierzchala - Analytical Biochemistry, 2022 - Elsevier
Oxidative stress is a natural phenomenon in the body. Under physiological conditions
intracellular reactive oxygen species (ROS) are normal components of signal transduction …

Novel near-infrared fluorescence probe for bioimaging and evaluating superoxide anion fluctuations in ferroptosis-mediated epilepsy

W Yang, R Liu, X Yin, K Wu, Z Yan, X Wang… - Analytical …, 2023 - ACS Publications
Ferroptosis is an iron-regulated, caspase-mediated pathway of cell death that is associated
with the excessive aggregation of lipid-reactive oxygen species and is extensively involved …

Contribution of non-selective membrane channels and receptors in epilepsy

C García-Rodríguez, ID Bravo-Tobar, Y Duarte… - Pharmacology & …, 2022 - Elsevier
Overcoming refractory epilepsy's resistance to the combination of antiepileptic drugs (AED),
mitigating side effects, and preventing sudden unexpected death in epilepsy are critical …

Unifying mechanism behind the onset of acquired epilepsy

Y Zilberter, I Popova, M Zilberter - Trends in pharmacological sciences, 2022 - cell.com
Acquired epilepsy (AE) can result from a number of brain insults and neurological diseases
with wide etiological diversity sharing one common outcome of brain epileptiform activity …

Selected biomarkers of oxidative stress and energy metabolism disorders in neurological diseases

I Korczowska-Łącka, M Hurła, N Banaszek… - Molecular …, 2023 - Springer
Neurological diseases can be broadly divided according to causal factors into circulatory
system disorders leading to ischemic stroke; degeneration of the nerve cells leading to …

Anticonvulsant potential of Grewia tiliaefolia in pentylenetetrazole induced epilepsy: insights from in vivo and in silico studies

A Rajput, P Sharma, N Kumar, H Singh, T Singh… - Metabolic Brain …, 2023 - Springer
Epilepsy, a chronic neurological condition, impacts millions of individuals globally and
remains a significant contributor to both illness and mortality. Available antiepileptic drugs …

Tanshinone-IIA mediated neuroprotection by modulating neuronal pathways

K Sherawat, S Mehan - Naunyn-Schmiedeberg's Archives of …, 2023 - Springer
The progression of neurological diseases is mainly attributed to oxidative stress, apoptosis,
inflammation, and trauma, making them a primary public concern. Since no drugs can stop …

Overview of the neuroprotective effects of the MAO-inhibiting antidepressant phenelzine

D Matveychuk, EM MacKenzie, D Kumpula… - Cellular and molecular …, 2022 - Springer
Phenelzine (PLZ) is a monoamine oxidase (MAO)-inhibiting antidepressant with anxiolytic
properties. This multifaceted drug has a number of pharmacological and neurochemical …

Genistein protects epilepsy-induced brain injury through regulating the JAK2/STAT3 and Keap1/Nrf2 signaling pathways in the developing rats

Q Hu, H Yan, F Peng, W Feng, F Chen, X Huang… - European Journal of …, 2021 - Elsevier
Background Epilepsy is a common chronic neurological disease. Recurrent seizures can
cause irreversible brain damage. This study aimed to explore the regulation of Genistein on …