Progress and development of carbazole scaffold based as potential anti-alzheimer agents using MTDL approach

N Kumar, P Gupta, S Bansal - Letters in Drug Design & …, 2022 - ingentaconnect.com
Alzheimer's is a neurodegenerative disease (NDs) found in old age people with associated
most common symptom dementia. MTDLs (Multi-Target Direct Ligand strategy) is based on …

Insight into structural topology and supramolecular assembly of tetrahydrocarbazole-carbonitrile: On the importance of noncovalent interactions and urease inhibitory …

S Zaib, A Ibrar, I Khan, N Rana, RM Gomila… - Journal of Molecular …, 2023 - Elsevier
Organic crystals hold a significant importance in pharmaceuticals, biological systems and
functional materials. In the present study, a tricyclic aromatic structure, tetrahydrocarbazole …

A review on synthesis methods of tricyclic 1, 2, 3, 4-tetrahydrocarbazoles

N Kumar, V Kumar, Y Chowdhary - World Journal of Advanced Research …, 2022 - wjarr.com
In this review article, we discussed old to new synthetic methods used for the preparation of
1, 2, 3, 4-Tetrahydrocarbazole (THCz) based on reported literature. Around the worldwide …

DABCO-Promoted Cyclization of 2-Amino-4H-chromen-4-ones with 2,6-Dibenzylidenecyclohexan-1-ones for the Synthesis of Chromeno[2,3-b]tetrahydroquinoline

Y Xue, J Gan, N Luo, C Wang - The Journal of Organic Chemistry, 2022 - ACS Publications
DABCO-promoted cyclization reaction of substituted 2-amino-4 H-chromen-4-ones with
substituted 2, 6-dibenzylidenecyclohexan-1-ones was investigated under mild conditions …

Crescent‐Shaped Carbazole Derivatives as Light‐Up Fluorescence Probes for G‐Quadruplex DNA and Live Cell Imaging

Y Kang, C Wei - Chemistry & Biodiversity, 2022 - Wiley Online Library
In recent years, studies on the organic small molecule fluorescent probes targeting G‐
quadruplexes have attracted a wide attention, because G‐quadruplexes play an important …

[HTML][HTML] Diverse pharmacological actions of potential carbazole derivatives by influencing various pathways of molecular signaling

A Tiwari, B Mishra - Future Journal of Pharmaceutical …, 2024 - fjps.springeropen.com
Carbazoles are an important class of heterocyclic aromatic compounds that contain nitrogen
atom in the ring. They have a large-conjugated system, attractive “electrical and charge …

Anticancer Tetrahydrocarbazoles: A Wide Journey from 2000 Till Date

N Kumar, P Gupta - Letters in Drug Design & Discovery, 2024 - ingentaconnect.com
Tetrahydrocarbazoles (THCz) are widespread in numerous indole alkaloids and have been
reported since time for exhibiting profound pharmacological potential. Many …

Synthesis of chromeno[2,3-b]indeno[2,1-e]pyridine derivatives via K2CO3-promoted three-component reaction of 2-amino-4H-chromen-4-ones, aromatic aldehydes and 1H …

W Zhou, J Gan, C Wu, X Shen… - Synthetic Communications, 2023 - Taylor & Francis
An efficient process to access chromeno-fused azafluorenones (chromeno [2, 3-b] indeno [2,
1-e] pyridine) via the three-component reaction between 2-amino-4 H-chromen-4-ones …

A Review of In Vitro Antimicrobial Activities of Carbazole and its Derivative From 2014 to 2022

N Kumar, S Sharma, P Nirmal - Anti-Infective Agents, 2023 - ingentaconnect.com
A large number of antibiotics are easily accessible for the treatment of various microbial
infections. However, antibiotic resistance has become a major concern to public health …

Synthesis and anticancer activity evaluation of substituted carbazole bearing thiosemicarbazide derivatives against human glioma U87 MG cell line

N Kumar, V Nemaysh, PM Luthra - World Journal of Advanced Research …, 2022 - wjarr.com
Both carbazole and thiosemicarbazide scaffold showed various potential biological activities
in medicinal chemistry. In this research work, we synthesized a series of carbazole bearing …