[HTML][HTML] Inflammatory responses and inflammation-associated diseases in organs

L Chen, H Deng, H Cui, J Fang, Z Zuo, J Deng, Y Li… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Inflammation is a biological response of the immune system that can be triggered by a
variety of factors, including pathogens, damaged cells and toxic compounds. These factors …

Pathogenesis of acute respiratory distress syndrome

LA Huppert, MA Matthay… - Seminars in respiratory and …, 2019 - thieme-connect.com
Acute respiratory distress syndrome (ARDS) is a syndrome of acute respiratory failure
caused by noncardiogenic pulmonary edema. Despite five decades of basic and clinical …

[HTML][HTML] Overview: systemic inflammatory response derived from lung injury caused by SARS-CoV-2 infection explains severe outcomes in COVID-19

RB Polidoro, RS Hagan, R de Santis Santiago… - Frontiers in …, 2020 - frontiersin.org
Most SARS-CoV2 infections will not develop into severe COVID-19. However, in some
patients, lung infection leads to the activation of alveolar macrophages and lung epithelial …

Hypoxia: A key feature of COVID-19 launching activation of HIF-1 and cytokine storm

M Jahani, S Dokaneheifard, K Mansouri - Journal of inflammation, 2020 - Springer
COVID-19, disease caused by the new coronavirus, SARS-CoV-2, appeared in the end of
2019 and was rapidly spread in most countries. This respiratory virus has different symptoms …

The acute respiratory distress syndrome

MA Matthay, LB Ware… - The Journal of clinical …, 2012 - Am Soc Clin Investig
The acute respiratory distress syndrome (ARDS) is an important cause of acute respiratory
failure that is often associated with multiple organ failure. Several clinical disorders can …

New insights into the immunology of chronic obstructive pulmonary disease

GG Brusselle, GF Joos, KR Bracke - The Lancet, 2011 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome associated
with abnormal inflammatory immune responses of the lung to noxious particles and gases …

[HTML][HTML] Epithelial MHC class II expression and its role in antigen presentation in the gastrointestinal and respiratory tracts

JE Wosen, D Mukhopadhyay, C Macaubas… - Frontiers in …, 2018 - frontiersin.org
As the primary barrier between an organism and its environment, epithelial cells are well-
positioned to regulate tolerance while preserving immunity against pathogens. Class II …

Oxidative stress and cellular pathways of asthma and inflammation: Therapeutic strategies and pharmacological targets

V Mishra, J Banga, P Silveyra - Pharmacology & Therapeutics, 2018 - Elsevier
Asthma is a complex inflammatory disease characterized by airway inflammation and
hyperresponsiveness. The mechanisms associated with the development and progression …

The acute respiratory distress syndrome

LB Ware, MA Matthay - New England Journal of Medicine, 2000 - Mass Medical Soc
The acute respiratory distress syndrome is a common, devastating clinical syndrome of
acute lung injury that affects both medical and surgical patients. Since the last review of this …

[HTML][HTML] Lung epithelial cells: therapeutically inducible effectors of antimicrobial defense

MM Leiva-Juárez, JK Kolls, SE Evans - Mucosal immunology, 2018 - Elsevier
Lung epithelial cells are increasingly recognized to be active effectors of microbial defense,
contributing to both innate and adaptive immune function in the lower respiratory tract. As …