Near-infrared luminescence high-contrast in vivo biomedical imaging

Y Chen, S Wang, F Zhang - Nature Reviews Bioengineering, 2023 - nature.com
Luminescence imaging in biomedical research has allowed new insights into the
architecture of pathological tissues, signalling networks and cell interactions, and is now …

[HTML][HTML] Recent progress in the development of fluorescent probes for imaging pathological oxidative stress

Y Geng, Z Wang, J Zhou, M Zhu, J Liu… - Chemical Society …, 2023 - pubs.rsc.org
Oxidative stress is closely related to the physiopathology of numerous diseases. Reactive
oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS) …

Stable, bright, and long-fluorescence-lifetime dyes for deep-near-infrared bioimaging

J Li, Y Dong, R Wei, G Jiang, C Yao, M Lv… - Journal of the …, 2022 - ACS Publications
Near-infrared (NIR) fluorophores absorbing maximally in the region beyond 800 nm, ie,
deep-NIR spectral region, are actively sought for biomedical applications. Ideal dyes are …

Engineering of reversible NIR‐II redox‐responsive fluorescent probes for imaging of inflammation in vivo

L He, LH He, S Xu, TB Ren, XX Zhang… - Angewandte …, 2022 - Wiley Online Library
The second near‐infrared (NIR‐II) fluorescent imaging shows great potential for deep tissue
analysis at high resolution in living body owing to low background autofluorescence and …

Polymethine molecular platform for ratiometric fluorescent probes in the second near-infrared window

Q Lan, P Yu, K Yan, X Li, F Zhang… - Journal of the American …, 2022 - ACS Publications
Visualizing biomolecules such as enzymes in the deep tissue of living organisms via
molecular ratiometric fluorescent probes in the second near-infrared window (NIR-II) with a …

A Near‐Infrared Light‐Activated Photocage Based on a Ruthenium Complex for Cancer Phototherapy

G He, M He, R Wang, X Li, H Hu… - Angewandte Chemie …, 2023 - Wiley Online Library
Conventional photocages only respond to short wavelength light, which is a significant
obstacle to developing efficient phototherapy in vivo. The development of photocages …

Design of NIR-II high performance organic small molecule fluorescent probes and summary of their biomedical applications

X Liu, B Yu, Y Shen, H Cong - Coordination Chemistry Reviews, 2022 - Elsevier
Near-infrared fluorescence imaging has gained a lot of attention in biomedicine by virtue of
its high sensitivity, high specificity, and many other advantages. Moreover, near-infrared II …

NIRII‐HDs: A Versatile Platform for Developing Activatable NIR‐II Fluorogenic Probes for Reliable In Vivo Analyte Sensing

Z Qin, TB Ren, H Zhou, X Zhang, L He… - Angewandte Chemie …, 2022 - Wiley Online Library
Small‐molecule‐based second near‐infrared (NIR‐II) activatable fluorescent probes can
potentially provide a high target‐to‐background ratio and deep tissue penetration. However …

Counterion‐Paired Bright Heptamethine Fluorophores with NIR‐II Excitation and Emission Enable Multiplexed Biomedical Imaging

Y Yang, C Sun, S Wang, K Yan, M Zhao… - Angewandte …, 2022 - Wiley Online Library
Photon excitation and emission at the NIR‐II spectral window enable high‐contrast deep‐
tissue bioimaging. However, multiplexed imaging with NIR‐II excitation and emission has …

[HTML][HTML] The pursuit of polymethine fluorophores with NIR-II emission and high brightness for in vivo applications

X Zhao, F Zhang, Z Lei - Chemical Science, 2022 - pubs.rsc.org
Polymethine cyanine dyes, as the most important class of organic near-infrared-II (NIR-II)
fluorophores, recently received increasing attention due to their high molar extinction …