Highlights•New fluorophores with optimised photophysical properties for in vivo
imaging.•Near-infrared-emitting fluorophore scaffolds that can be modularly functionalised.• …

Metallacages with suitable cavities and specific functions are promising delivery vectors in
biological systems. Herein, we report a morpholine-functionalized metallacage for lysosome …

Reactive oxygen species (ROS), a chemically defined group of reactive molecules derived
from molecular oxygen, are involved in a variety of physiological and pathological …

Early monitoring of gastrointestinal diseases via orally delivered NIR-II ratiometric
fluorescent probes represents a promising noninvasive diagnostic modality, but is …

Real-time fluorescence sensing can provide insight into biodynamics. However, few
fluorescent tools are available to overcome the tissue scattering and autofluorescence …

Ratiometric fluorescent probes could effectively offset the changes of the autofluorescence
and compartmental localization. FRET, ICT, etc. are the common strategies to design probes …

Excessive accumulation of reactive oxygen species (ROS) can lead to oxidative stress and
oxidative damage, which is one of the important factors for aging and age‐related diseases …

Tumor-associated macrophages, especially M2-like macrophages, are extensively involved
in tumor growth and metastasis, suppressing the innate immunity to help tumor cells escape …

Atherosclerosis (AS) is a major pathological factor to cardiovascular diseases, wherein
reactive oxygen species (ROS) serve as the initiating link for the development of AS …

Fluorescence imaging in the second near-infrared region (NIR-II) shows great potentials in
intravital imaging and analysis due to its high penetration depth and low photo-damage …