Background Rheumatoid arthritis (RA) is an autoimmune disease caused by a variety of
unknown factors. It mainly occurs in the small joints of hands and feet, leading to cartilage …

Osteoporosis (OP) is a metabolic bone disease characterized by decreased bone mass and
increased bone fragility. The imbalance of bone homeostasis modulated by osteoclasts and …

Aberrant bone marrow mesenchymal stem cell (BMSC) lineage differentiation leads to
osteoporosis. Codonopsis pilosula polysaccharides (CPPs) have been widely used in …

Adipose tissue plays a crucial role in maintaining energy balance, regulating hormones, and
promoting metabolic health. To address disorders related to obesity and develop effective …

Alteration of N6-methyladenosine (m6A) is closely linked to spanning biological processes
including osteoporosis (OP) development. This research focuses on the function of …

Bone acts as a self-healing organ, which undergoes continuous regeneration process that is
tightly regulated by the cooperation of osteoclasts with the capability of bone resorption and …

The objective of this study is to explore the specific roles of a crucial N6-methyladenosine
(m6A) methyltransferase, methyltransferase-like 14 (METTL14), in fibroblast-like …

Osteoporosis (OP) is a severe global health issue that has significant implications for
productivity and human lifespan. Gut microbiota dysbiosis has been demonstrated to be …

Senile osteoporosis is mainly caused by osteoblasts attenuation, which results in reduced
bone mass and disrupted bone remodeling. Numerous studies have focused on the …

Digestive tract cancers are among the most common malignancies worldwide and have high
incidence and mortality rates. Thus, the discovery of more effective diagnostic and …