The most widespread intracellular bacteria in the animal kingdom are maternally inherited
endosymbionts of the genus Wolbachia. Their prevalence in arthropods and nematodes …

Mosquito-borne diseases, such as dengue and malaria, pose significant global health
burdens. Unfortunately, current control methods based on insecticides and environmental …

Background Aedes aegypti mosquitoes infected with the w Mel strain of Wolbachia pipientis
are less susceptible than wild-type A. aegypti to dengue virus infection. Methods We …

Background Dengue is an arboviral disease caused by dengue virus. Symptomatic dengue
infection causes a wide range of clinical manifestations, from mild dengue fever (DF) to …

Releasing sterile or incompatible male insects is a proven method of population
management in agricultural systems with the potential to revolutionize mosquito control …

Background The introduction of the bacterium Wolbachia (w Mel strain) into Aedes aegypti
mosquitoes reduces their capacity to transmit dengue and other arboviruses. Evidence of a …

Background: Ae. aegypti mosquitoes stably transfected with the intracellular bacterium
Wolbachia pipientis (wMel strain) have been deployed for biocontrol of dengue and related …

Mosquito-borne diseases are an increasing global health challenge, threatening over 40%
of the world's population. Despite major advances in malaria control since 2000, recent …

Mosquitoes carrying Wolbachia endosymbionts are being released in many countries for
arbovirus control. The wMel strain of Wolbachia blocks Aedes-borne virus transmission and …

In this review we examine how exploiting the Wolbachia–mosquito relationship has become
an increasingly popular strategy for controlling arbovirus transmission. Field deployments of …