Organoids: The current status and biomedical applications

S Yang, H Hu, H Kung, R Zou, Y Dai, Y Hu… - MedComm, 2023 - Wiley Online Library
Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …

Intestinal organoids and organoids extracellular vesicles for inflammatory bowel disease treatment

H Liu, J Sun, M Wang, S Wang, J Su, C Xu - Chemical Engineering Journal, 2023 - Elsevier
Inflammatory bowel disease (IBD), a chronic inflammatory disease of the gastrointestinal
tract, is characterized by abdominal pain, diarrhea, and bloody stools, posing a serious …

[HTML][HTML] Single-cell mapping of lipid metabolites using an infrared probe in human-derived model systems

Y Bai, CM Camargo, SMK Glasauer, R Gifford… - Nature …, 2024 - nature.com
Understanding metabolic heterogeneity is the key to uncovering the underlying mechanisms
of metabolic-related diseases. Current metabolic imaging studies suffer from limitations …

Organoid: Bridging the gap between basic research and clinical practice

G Weng, J Tao, Y Liu, J Qiu, D Su, R Wang, W Luo… - Cancer Letters, 2023 - Elsevier
Nowadays, the diagnosis and treatment system of malignant tumors has increasingly tended
to be more precise and personalized. And the existing tumor models are still unable to fully …

[HTML][HTML] Non-alcoholic fatty liver disease and diabetes mellitus as growing aetiologies of hepatocellular carcinoma

S Talamantes, M Lisjak, EH Gilglioni… - JHEP Reports, 2023 - Elsevier
Obesity-related complications such as non-alcoholic fatty liver disease (NAFLD) and type 2
diabetes (T2D) are well-established risk factors for the development of hepatocellular …

Advanced 3D imaging and organoid bioprinting for biomedical research and therapeutic applications

S Maharjan, C Ma, B Singh, H Kang, G Orive… - Advanced Drug Delivery …, 2024 - Elsevier
Organoid cultures offer a valuable platform for studying organ-level biology, allowing for a
closer mimicry of human physiology compared to traditional two-dimensional cell culture …

Artificial Neural Processing‐Driven Bioelectronic Nose for the Diagnosis of Diabetes and Its Complications

WB Jang, D Yi, TM Nguyen, Y Lee… - Advanced …, 2023 - Wiley Online Library
Diabetes and its complications affect the younger population and are associated with a high
mortality rate; however, early diagnosis can contribute to the selection of appropriate …

Engineering in vitro models: Bioprinting of organoids with artificial intelligence

H Lee - Cyborg and Bionic Systems, 2023 - spj.science.org
In the last decade, organoids have gained popularity for developing mini-organs to support
advancements in the study of organogenesis, disease modeling, and drug screening and …

Emerging trends in the methodology of environmental toxicology: 3D cell culture and its applications

H Wang, T Xu, D Yin - Science of The Total Environment, 2023 - Elsevier
Human diseases and health concerns caused by environmental pollutants are globally
emerging. Therefore, rapid and efficient evaluation of the effects of environmental pollutants …

Recent advances in liver‐on‐chips: Design, fabrication, and applications

L Qiu, B Kong, T Kong, H Wang - Smart Medicine, 2023 - Wiley Online Library
The liver is a multifunctional organ and the metabolic center of the human body. Most drugs
and toxins are metabolized in the liver, resulting in varying degrees of hepatotoxicity. The …