Research progress of natural Matrine compounds and synthetic Matrine derivatives

J Li, S Wei, D Marabada, Z Wang, Q Huang - Molecules, 2023 - mdpi.com
Matrine is a quinoline alkaloid extracted and separated from the dried root, fruit, and other
parts of the plant Sophora flavescens using an organic solvent. Matrine exhibits a variety of …

Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives

HI Abd-Alla, D Souguir, MO Radwan - Archives of pharmacal research, 2021 - Springer
Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third
largest family of flowering plants. The genus Sophora comprises approximately 52 species …

Recent advances for alkaloids as botanical pesticides for use in organic agriculture

Y Wu, D Ren, C Gao, J Li, B Du, Z Wang… - International Journal of …, 2021 - Taylor & Francis
Alkaloids are the most basic organic compounds involved in crucial physiological activities
and are widely found in plants, animals and microorganisms. Due to the anti-inflammatory …

Quinolizidine alkaloids from Sophora alopecuroides with anti-inflammatory and anti-tumor properties

JC Li, WF Dai, D Liu, ZJ Zhang, MY Jiang, KR Rao… - Bioorganic …, 2021 - Elsevier
Abstract Forty-three quinolizidine alkaloids (1–43), including twelve new matrine-type ones,
sophalodes A–L (1–7, 17, 19 and 28–30), were isolated from the seeds of Sophora …

Dolabrane-Type Diterpenoids with Immunosuppressive Activity from Koilodepas hainanense

Y Ren, X Tong, Y Zhao, SJ He, YY Fan… - Journal of Natural …, 2022 - ACS Publications
Thirteen new dolabrane-type diterpenoids, koilodenoids A–M (1–13), including a
chlorinated congener (2), along with six known analogues, were isolated from Koilodepas …

Structurally Diverse Matrine‐Based Alkaloids with Anti‐inflammatory Effects from Sophora alopecuroides

D Luo, NH Chen, WZ Wang, JH Zhang… - Chinese Journal of …, 2021 - Wiley Online Library
Main observation and conclusion A phytochemical investigation on the seeds of Sophora
alopecuroides led to obtaining fourteen structurally diverse matrine‐based alkaloids (1 …

Water-soluble matrine-type alkaloids with potential anti-neuroinflammatory activities from the seeds of Sophora alopecuroides

D Luo, Q Lin, JL Tan, HY Zhao, X Feng, NH Chen… - Bioorganic …, 2021 - Elsevier
A phytochemical investigation on the alkaloids from water-soluble part of Sophora
alopecuroides led to obtain forty matrine-type alkaloids (1–40) including eighteen new ones …

Biological activity of naturally derived naphthyridines

G Chabowska, E Barg, A Wójcicka - Molecules, 2021 - mdpi.com
Marine and terrestrial environments are rich sources of various bioactive substances, which
have been used by humans since prehistoric times. Nowadays, due to advances in chemical …

Research Progress of Natural Active Substances with Immunosuppressive Activity

F Shao, Q Shen, Z Yang, W Yang, Z Lu, J Zheng… - Molecules, 2024 - mdpi.com
The increasing prevalence of autoimmune diseases globally has prompted extensive
research and the development of immunosuppressants. Currently, immunosuppressive …

Pterocarpans and 2-arylbenzofurans from Sophora flavescens aiton and their chemotaxonomic significance

XY Du, GX Li, XQ Chen, RT Li, ZJ Zhang - Biochemical Systematics and …, 2022 - Elsevier
Phytochemical investigation of the root of Sophora flavescens Ait. led to the isolation of
previously uncharacterized pterocarpan derivative sophoracarpanol A (1), along with eight …