[HTML][HTML] The biological and clinical aspects of a latent tuberculosis infection
NF Khabibullina, DM Kutuzova, IA Burmistrova… - Tropical medicine and …, 2022 - mdpi.com
Tuberculosis (TB), caused by bacilli from the Mycobacterium tuberculosis complex, remains
a serious global public health problem, representing one of the main causes of death from …
a serious global public health problem, representing one of the main causes of death from …
[HTML][HTML] Contribution and future of high-throughput transcriptomics in battling tuberculosis
A Martínez-Pérez, O Estévez… - Frontiers in …, 2022 - frontiersin.org
While Tuberculosis (TB) infection remains a serious challenge worldwide, big data and
“omic” approaches have greatly contributed to the understanding of the disease …
“omic” approaches have greatly contributed to the understanding of the disease …
Systems-level profiling of early peripheral host-response landscape variations across COVID-19 severity states in an Indian cohort
U Banerjee, S Chunchanur, KN Balaji, A Singh… - Genes & …, 2023 - nature.com
Host immune response to COVID-19 plays a significant role in regulating disease severity.
Although big data analysis has provided significant insights into the host biology of COVID …
Although big data analysis has provided significant insights into the host biology of COVID …
[HTML][HTML] Exploring optimal drug targets through subtractive proteomics analysis and pangenomic insights for tailored drug design in tuberculosis
Tuberculosis (TB), caused by Mycobacterium tuberculosis, ranks among the top causes of
global human mortality, as reported by the World Health Organization's 2022 TB report. The …
global human mortality, as reported by the World Health Organization's 2022 TB report. The …
The significance of persisters in tuberculosis drug discovery: Exploring the potential of targeting the glyoxylate shunt pathway
The significant challenge in confronting TB eradication is the discursive treatment that
results in the disease reactivation, patient non compliance and drug resistance. The …
results in the disease reactivation, patient non compliance and drug resistance. The …
Latent tuberculosis and computational biology: A less-talked affair
Tuberculosis (TB) is a pervasive and devastating air-borne disease caused by the
organisms belonging to the Mycobacterium tuberculosis (Mtb) complex. Currently, it is the …
organisms belonging to the Mycobacterium tuberculosis (Mtb) complex. Currently, it is the …
PathTracer Comprehensively Identifies Hypoxia-Induced Dormancy Adaptations in Mycobacterium tuberculosis
U Banerjee, A Chedere, R Padaki… - Journal of Chemical …, 2023 - ACS Publications
Mining large-scale data to discover biologically relevant information remains a challenge
despite the rapid development of bioinformatics tools. Here, we have developed a new tool …
despite the rapid development of bioinformatics tools. Here, we have developed a new tool …
Inhibition of leukotriene‐B4 signalling‐mediated host response to tuberculosis is a potential mode of adjunctive host‐directed therapy
U Banerjee, SM Borbora, M Guha, V Yadav… - …, 2024 - Wiley Online Library
Abstract Treatment of tuberculosis (TB) is faced with several challenges including the long
treatment duration, drug toxicity and tissue pathology. Host‐directed therapy provides …
treatment duration, drug toxicity and tissue pathology. Host‐directed therapy provides …
Evaluation of a novel inhibitor of aspartate semialdehyde dehydrogenase as a potent antitubercular agent against Mycobacterium tuberculosis
R Yang, W Cao, S Liu, Q Li, Y Sun, C Liang… - The Journal of …, 2022 - nature.com
The in vitro activity of IMB-XMA0038, a novel inhibitor targeting Mycobacterial tuberculosis
(Mtb) aspartate semialdehyde dehydrogenase, was evaluated. Minimum inhibitory …
(Mtb) aspartate semialdehyde dehydrogenase, was evaluated. Minimum inhibitory …
[HTML][HTML] Protein Integrated Network Analysis to Reveal Potential Drug Targets Against Extended Drug-Resistant Mycobacterium tuberculosis XDR1219
The reconstruction and analysis of the protein–protein interaction (PPI) network is a powerful
approach to understand the complex biological and molecular functions in normal and …
approach to understand the complex biological and molecular functions in normal and …