Effective gene delivery using stimulus-responsive catiomer designed with redox-sensitive disulfide and acid-labile imine linkers
X Cai, C Dong, H Dong, G Wang, GM Pauletti… - …, 2012 - ACS Publications
A dual stimulus-responsive mPEG-SS-PLL15-glutaraldehyde star (mPEG-SS-PLL15-star)
catiomer is developed and biologically evaluated. The catiomer system combines redox …
catiomer is developed and biologically evaluated. The catiomer system combines redox …
Hydrophobic modification of low molecular weight polyethylenimine for improved gene transfection
Hydrophobic modification of low molecular weight (LMW) polyethylenimine (PEI) is known to
increase gene transfection efficiency of LMW PEI. However, few studies have explored how …
increase gene transfection efficiency of LMW PEI. However, few studies have explored how …
Virus-inspired nucleic acid delivery system: linking virus and viral mimicry
Targeted delivery of nucleic acids into disease sites of human body has been attempted for
decades, but both viral and non-viral vectors are yet to meet our expectations. Safety …
decades, but both viral and non-viral vectors are yet to meet our expectations. Safety …
Degradable polyethylenimines as DNA and small interfering RNA carriers
D Jere, HL Jiang, R Arote, YK Kim, YJ Choi… - Expert opinion on …, 2009 - Taylor & Francis
Gene therapy is a powerful approach in the treatment of a wide range of both inherited and
acquired diseases. Nonviral delivery systems have been proposed as safer alternatives to …
acquired diseases. Nonviral delivery systems have been proposed as safer alternatives to …
Constructing multi-component organic/inorganic composite bacterial cellulose-gelatin/hydroxyapatite double-network scaffold platform for stem cell-mediated bone …
J Ran, P Jiang, S Liu, G Sun, P Yan, X Shen… - Materials Science and …, 2017 - Elsevier
Bacterial cellulose/hydroxyapatite (BC/HAp) composite had good bioaffinity but its poor
mechanical strength limited its widespread applications in bone tissue engineering (BTE) …
mechanical strength limited its widespread applications in bone tissue engineering (BTE) …
Non-viral gene delivery carrier and its three-dimensional transfection system
CX He, Y Tabata, JQ Gao - International journal of pharmaceutics, 2010 - Elsevier
An increasing number of non-viral vectors are being developed for the use of gene delivery
nowadays, among which cationic polymers and lipoplexes receive most attention. Most of …
nowadays, among which cationic polymers and lipoplexes receive most attention. Most of …
Dual-functional dendrimer micelles with glycyrrhizic acid for anti-inflammatory therapy of acute lung injury
Dendrimer micelles with glycyrrhizic acid (GA) were developed for anti-inflammatory therapy
of acute lung injury (ALI). Cholesterol was conjugated to histidine-and arginine-grafted …
of acute lung injury (ALI). Cholesterol was conjugated to histidine-and arginine-grafted …
Exploring the role of polymer structure on intracellular nucleic acid delivery via polymeric nanoparticles
Intracellular nucleic acid delivery has the potential to treat many genetically-based diseases,
however, gene delivery safety and efficacy remains a challenging obstacle. One promising …
however, gene delivery safety and efficacy remains a challenging obstacle. One promising …
Polymeric biomaterials with engineered degradation
S Deshayes, AM Kasko - Journal of Polymer Science Part A …, 2013 - Wiley Online Library
Polymeric biomaterials are widely used as carriers for cells and therapeutic agents. Until
recently, most research has been limited to a relatively narrow number of monomers and …
recently, most research has been limited to a relatively narrow number of monomers and …
Bioelectricity for drug delivery: the promise of cationic therapeutics
Biological systems overwhelmingly comprise charged entities generating electrical activity
that can have significant impact on biological structure and function. This intrinsic bio …
that can have significant impact on biological structure and function. This intrinsic bio …