Nowadays, biomaterials have evolved from the inert supports or functional substitutes to the
bioactive materials able to trigger or promote the regenerative potential of tissues. The …

The native extracellular matrix (ECM) generally exhibits dynamic mechanical properties and
displays time‐dependent responses to deformation or mechanical loading, in terms of …

An appropriate cell microenvironment is key to tissue engineering and regenerative
medicine. Revealing the factors that influence the cell microenvironment is a fundamental …

Stem cells hold great promise for widespread biomedical applications, for which stem cell
fate needs to be well tailored. Besides biochemical cues, accumulating evidence has …

The mechanical properties of the microenvironment and direct contact-mediated cell-cell
interactions are two variables known to be important in the determination of stem cell …

Owing to their self‐renewal and differentiation ability, stem cells are conducive for repairing
injured tissues, making them a promising source of seed cells for tissue engineering. The …

Bone and cartilage injury is common, tissue engineered scaffolds are potential means to
repair. Because most of the scaffold materials used in bone and cartilage tissue engineering …

Surface topography is a biophysical factor affecting cell behaviors, yet the underlying cues
are still not clear. Herein, we hypothesized that stereo coverage and overall stiffness of …

dimensional (3D) bioprinting technology provides promising strategy in the fabrication of
artificial tissues and organs. As the fundamental element in bioprinting process, preparation …

While various static cues such as matrix stiffness have been known to regulate stem cell
differentiation, it is unclear whether or not dynamic cues such as degradation rate along with …