Pseudomonas aeruginosa : new insights into pathogenesis and host defenses

SL Gellatly, REW Hancock - Pathogens and disease, 2013 - academic.oup.com
Pseudomonas aeruginosa is a metabolically versatile bacterium that can cause a wide
range of severe opportunistic infections in patients with serious underlying medical …

Overview of mechanisms of antibiotic resistance in Pseudomonas aeruginosa: an ocular perspective

D Subedi, AK Vijay, M Willcox - Clinical and Experimental …, 2018 - Taylor & Francis
Treatment of Pseudomonas aeruginosa eye infections often becomes a challenge due to the
ability of this bacterium to be resistant to antibiotics via intrinsic and acquired mechanisms …

Silver nanoparticles impede the biofilm formation by Pseudomonas aeruginosa and Staphylococcus epidermidis

K Kalishwaralal, S BarathManiKanth… - Colloids and Surfaces B …, 2010 - Elsevier
Biofilms are ensued due to bacteria that attach to surfaces and aggregate in a hydrated
polymeric matrix. Formation of these sessile communities and their inherent resistance to …

[HTML][HTML] A signaling network reciprocally regulates genes associated with acute infection and chronic persistence in Pseudomonas aeruginosa

AL Goodman, B Kulasekara, A Rietsch, D Boyd… - Developmental cell, 2004 - cell.com
The opportunistic pathogen Pseudomonas aeruginosa causes a variety of acute and chronic
infections. We identified a gene whose inactivation results in attenuation of virulence due to …

[HTML][HTML] What's on the outside matters: the role of the extracellular polymeric substance of Gram-negative biofilms in evading host immunity and as a target for …

JS Gunn, LO Bakaletz, DJ Wozniak - Journal of Biological Chemistry, 2016 - ASBMB
Biofilms are organized multicellular communities encased in an extracellular polymeric
substance (EPS). Biofilm-resident bacteria resist immunity and antimicrobials. The EPS …

Incidence of keratitis of varying severity among contact lens wearers

PB Morgan, N Efron, EA Hill, MK Raynor… - British Journal of …, 2005 - bjo.bmj.com
Aim: To determine the incidence of non-severe keratitis (NSK) and severe keratitis (SK)
among wearers of current generation contact lenses. Methods: A 12 month, prospective …

[HTML][HTML] A Novel Signaling Network Essential for Regulating Pseudomonas aeruginosa Biofilm Development

OE Petrova, K Sauer - PLoS pathogens, 2009 - journals.plos.org
The important human pathogen Pseudomonas aeruginosa has been linked to numerous
biofilm-related chronic infections. Here, we demonstrate that biofilm formation following the …

Internalization of Pseudomonas aeruginosa strain PAO1 into epithelial cells is promoted by interaction of a T6SS effector with the microtubule network

TG Sana, C Baumann, A Merdes, C Soscia, T Rattei… - MBio, 2015 - Am Soc Microbiol
Invasion of nonphagocytic cells through rearrangement of the actin cytoskeleton is a
common immune evasion mechanism used by most intracellular bacteria. However, some …

Cellular and extracellular matrix modulation of corneal stromal opacity

AAM Torricelli, SE Wilson - Experimental eye research, 2014 - Elsevier
Stromal transparency is a critical factor contributing to normal function of the visual system.
Corneal injury, surgery, disease and infection elicit complex wound healing responses that …

[HTML][HTML] Ocular Bacterial Infections: A ten-year survey and review of causative organisms based on the oklahoma experience

RA Astley, MH Mursalin, PS Coburn, ET Livingston… - Microorganisms, 2023 - mdpi.com
Ocular infections can be medical emergencies that result in permanent visual impairment or
blindness and loss of quality of life. Bacteria are a major cause of ocular infections. Effective …