Adolescents and young adults with cancer: the scope of the problem and criticality of clinical trials

A Bleyer, T Budd, M Montello - … International Journal of the …, 2006 - Wiley Online Library
In the US, older adolescents and young adults with cancer have benefited less from
therapeutic advances than did either younger or older patients. One factor that may explain …

The management of cancer in the older adolescent

K Albritton, WA Bleyer - European Journal of Cancer, 2003 - Elsevier
Cancer in adolescents 15–19 years of age occurs at nearly twice the rate observed in 5-to
14-year-olds, but as of yet they have no explicit organisation for research and care, such as …

Initial diagnostic workup of acute leukemia: guideline from the College of American Pathologists and the American Society of Hematology

DA Arber, MJ Borowitz, M Cessna… - … of pathology & …, 2017 - meridian.allenpress.com
Context.—A complete diagnosis of acute leukemia requires knowledge of clinical
information combined with morphologic evaluation, immunophenotyping and karyotype …

Results of a randomized trial in children with Acute Myeloid Leukaemia: medical research council AML12 trial

BES Gibson, DKH Webb, AJ Howman… - British journal of …, 2011 - Wiley Online Library
Summary The Medical Research Council Acute Myeloid Leukaemia 12 (MRC AML12) trial
(children) addressed the optimal anthracenedione/anthracycline in induction and the …

Racial disparities in the survival of American children, adolescents, and young adults with acute lymphoblastic leukemia, acute myelogenous leukemia, and Hodgkin …

JM Kahn, THM Keegan, L Tao, R Abrahão, A Bleyer… - Cancer, 2016 - Wiley Online Library
BACKGROUND Race‐based survival in children and adolescents with hematologic
malignancies has been a national challenge for decades. Large‐scale investigations of age …

Consequent and intensified relapse therapy improved survival in pediatric AML: results of relapse treatment in 379 patients of three consecutive AML-BFM trials

A Sander, M Zimmermann, M Dworzak, G Fleischhack… - Leukemia, 2010 - nature.com
Relapse remains the major cause of treatment failure in pediatric acute myeloid leukemia
(AML). We analyzed the clinical characteristics, treatment response to relapse treatment and …

High WT1 expression after induction therapy predicts high risk of relapse and death in pediatric acute myeloid leukemia

H Lapillonne, A Renneville, A Auvrignon… - Journal of clinical …, 2006 - ascopubs.org
Purpose To determine whether minimal residual disease (MRD) measured by Wilms' tumor
gene 1 (WT1) expression is a prognostic marker in pediatric acute myeloid leukemia (AML) …

Safety and efficacy of gemtuzumab ozogamicin in pediatric patients with advanced CD33+ acute myeloid leukemia

RJ Arceci, J Sande, B Lange, K Shannon, J Franklin… - Blood, 2005 - ashpublications.org
This open-label, dose-escalation study evaluated the safety and efficacy of single-agent
gemtuzumab ozogamicin, a humanized anti-CD33 antibody–targeted chemotherapeutic …

Incidence and survival rates of hematological malignancies in Japanese children and adolescents (2006–2010): based on registry data from the Japanese Society of …

K Horibe, AM Saito, T Takimoto, M Tsuchida… - International journal of …, 2013 - Springer
Neither accurate incidence nor survival data for pediatric patients with hematological
malignancies (HM) have been available in Japan to date. Incidence of patients under 20 …

Long-term results in children with AML: NOPHO-AML Study Group–report of three consecutive trials

SO Lie, J Abrahamsson, N Clausen, E Forestier… - Leukemia, 2005 - nature.com
In all, 447 children with acute myeloid leukaemia (AML) have been treated on three
consecutive NOPHO studies from July 1984 to December 2001. NOPHO-AML 84 was of …