The SARS-CoV-2 nucleocapsid protein: its role in the viral life cycle, structure and functions, and use as a potential target in the development of vaccines and …
W Wu, Y Cheng, H Zhou, C Sun, S Zhang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) continues to take a heavy toll on personal
health, healthcare systems, and economies around the globe. Scientists are expending …
health, healthcare systems, and economies around the globe. Scientists are expending …
A review of SARS-CoV-2 disease (COVID-19): pandemic in our time
N Al-Awwal, F Dweik, S Mahdi, M El-Dweik… - Pathogens, 2022 - mdpi.com
Development and deployment of biosensors for the rapid detection of the 2019 novel severe
acute respiratory syndrome—coronavirus 2 (SARS-CoV-2) are of utmost importance and …
acute respiratory syndrome—coronavirus 2 (SARS-CoV-2) are of utmost importance and …
Bioinformatics approaches identified dasatinib and bortezomib inhibit the activity of MCM7 protein as a potential treatment against human cancer
Abstract Minichromosome Maintenance Complex Component 7 (MCM7) is a key component
of the DNA replication licensing factor and hexamer MCM (MCM2–7) complex that regulates …
of the DNA replication licensing factor and hexamer MCM (MCM2–7) complex that regulates …
Cheminformatics-based identification of phosphorylated RET tyrosine kinase inhibitors for human cancer
Background Rearranged during transfection (RET), an oncogenic protein, is associated with
various cancers, including non-small-cell lung cancer (NSCLC), papillary thyroid cancer …
various cancers, including non-small-cell lung cancer (NSCLC), papillary thyroid cancer …
GC-MS analysis of phytoconstituents from Ruellia prostrata and Senna tora and identification of potential anti-viral activity against SARS-CoV-2
SARS-CoV-2 is an etiologic agent responsible for the coronavirus disease 2019 (COVID-19)
pandemic. The virus has rapidly extended globally and taken millions of lives due to the …
pandemic. The virus has rapidly extended globally and taken millions of lives due to the …
Computational formulation of a multiepitope vaccine unveils an exceptional prophylactic candidate against Merkel cell polyomavirus
Merkel cell carcinoma (MCC) is a rare neuroendocrine skin malignancy caused by human
Merkel cell polyomavirus (MCV), leading to the most aggressive skin cancer in humans …
Merkel cell polyomavirus (MCV), leading to the most aggressive skin cancer in humans …
Investigation of substituent effects on the electronic structure and antiviral activity of favipiravir derivatives for Covid-19 treatment using DFT and molecular docking
In this study, Density-functional theory/Time-dependent density-functional theory
(DFT/TDDFT) and Molecular docking method was used to investigate the effect of methyl …
(DFT/TDDFT) and Molecular docking method was used to investigate the effect of methyl …
Immune epitopes identification and designing of a multi-epitope vaccine against bovine leukemia virus: a molecular dynamics and immune simulation approaches
Background Bovine leukemia virus (BLV) is an oncogenic delta-retrovirus causing bovine
leucosis. Studies on BLV have shown the association with human breast cancer. However …
leucosis. Studies on BLV have shown the association with human breast cancer. However …
Toward the identification of natural antiviral drug candidates against merkel cell polyomavirus: computational drug design approaches
Merkel cell carcinoma (MCC) is a rare form of aggressive skin cancer mainly caused by
Merkel cell polyomavirus (MCPyV). Most MCC tumors express MCPyV large T (LT) antigens …
Merkel cell polyomavirus (MCPyV). Most MCC tumors express MCPyV large T (LT) antigens …
Assessing the potential contribution of in silico studies in discovering drug candidates that interact with various SARS-CoV-2 receptors
AGA Mushebenge, SC Ugbaja, NA Mbatha… - International Journal of …, 2023 - mdpi.com
The COVID-19 pandemic has spurred intense research efforts to identify effective treatments
for SARS-CoV-2. In silico studies have emerged as a powerful tool in the drug discovery …
for SARS-CoV-2. In silico studies have emerged as a powerful tool in the drug discovery …