Amongst the lysosomal cysteine cathepsin family of proteases, cathepsin S (CTSS) holds
particular interest due to distinctive properties including a normal restricted expression …

Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

The mechanisms involved in the induction of allergic sensitization by pollen are not fully
understood. Within the last few decades, findings from epidemiological and experimental …

Abstract This Scientific Opinion addresses the formulation of specific development needs,
including research requirements for allergenicity assessment and protein safety, in general …

Many allergens feature hydrophobic cavities that allow the binding of primarily hydrophobic
small‐molecule ligands. Ligand‐binding specificities can be strict or promiscuous. Serum …

There have been many attempts to identify common biophysical properties which
differentiate allergens from their non-immunogenic counterparts. This review will focus on …

The term allergy was coined in 1906 by the Austrian scientist and pediatrician Clemens
Freiherr von Pirquet. In 1976, Dietrich Kraft became the head of the Allergy and Immunology …

PR-10 proteins constitute a major cause of food allergic reactions. Birch-pollen-related food
allergies are triggered by the immunologic cross-reactivity of IgE antibodies with structurally …

About 10 years ago, a protein family was shown for the first time to contain allergenic
members, gibberellin-regulated protein (GRP). The first reported member was from peach …

Background White root rot disease in rubber trees, caused by the pathogenic fungi
Rigidoporus microporus, is currently considered a major problem in rubber tree plantations …