Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of
action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors …

Objectives To discuss the clinical pharmacology of currently licensed veterinary NSAIDs and
to review gastrointestinal and renal adverse effects as well as drug-drug interactions that …

Duloxetine, a serotonin and noradrenaline reuptake inhibitor, and celecoxib, a non-steroidal
anti-inflammatory drug, are commonly used analgesics for persistent pain, however with …

Background The aim of this study was to evaluate the effect of vitamin E co-administration
with celecoxib in thermal and inflammatory pain in two model of pain assessment including …

The non-steroidal anti-inflammatory drug celecoxib has long been used for reducing pain, in
spite of moderate gastrointestinal side effects. In previous studies, it has been shown that …

Pain is the most common complaint in the medical field and the identification of compounds
that can effectively treat painful states without induction of side‐effects remains a major …

BACKGROUND: Prostaglandins are synthesized by cyclooxygenase (COX) and are thought
to play an important role in nociceptive transmission in the spinal cord. Fos expression is an …

将千里光全草粉用体积分数70% 乙醇浸泡, 经超声波-微波处理, 用乙醚萃取脱色, 冷冻真空干燥,
制备千里光提取物冻干粉(SCE). 以对乙酰氨基酚为对照, 采用醋酸扭体法和热板法研究不同 …

Background In the present study we determined the antihyperalgesic and antiallodynic effect
of celecoxib in diabetic rats as well as the possible participation of opioid receptors in the …

Epidural injection of cyclooxygenase-2 inhibitors has been suggested as a useful
therapeutic modality in pain management in animal studies and clinical settings. Direct …