[HTML][HTML] Evaluation of antibiotic resistance mechanisms in gram-negative bacteria

A Gauba, KM Rahman - Antibiotics, 2023 - mdpi.com
Multidrug-resistant Gram-negative bacterial infections are exponentially increasing, posing
one of the most urgent global healthcare and economic threats. Due to the lack of new …

[HTML][HTML] Staphylococcus aureus biofilm: Formulation, regulatory, and emerging natural products-derived therapeutics

X Wu, H Wang, J Xiong, GX Yang, JF Hu, Q Zhu… - Biofilm, 2024 - Elsevier
Staphylococcus aureus can readily form biofilm which enhances the drug-resistance,
resulting in life-threatening infections involving different organs. Biofilm formation occurs due …

[HTML][HTML] Inhibition of multidrug efflux pumps belonging to the major facilitator superfamily in bacterial pathogens

MF Varela, J Stephen, D Bharti, M Lekshmi, S Kumar - Biomedicines, 2023 - mdpi.com
Bacterial pathogens resistant to multiple structurally distinct antimicrobial agents are
causative agents of infectious disease, and they thus constitute a serious concern for public …

[HTML][HTML] Medical device-associated healthcare infections: sterilization and the potential of novel biological approaches to ensure patient safety

M Garvey - International Journal of Molecular Sciences, 2023 - mdpi.com
Healthcare-associated infections caused by multi-drug-resistant pathogens are increasing
globally, and current antimicrobial options have limited efficacy against these robust …

[HTML][HTML] Identification of an antimicrobial peptide from the venom of the Trinidad thick-tailed scorpion Tityus trinitatis with potent activity against ESKAPE pathogens …

M Mechkarska, TS Cunning, MG Taggart, NG Ternan… - Antibiotics, 2023 - mdpi.com
Envenomation by the Trinidad thick-tailed scorpion Tityus trinitatis may result in fatal
myocarditis and there is a high incidence of acute pancreatitis among survivors. Peptidomic …

[HTML][HTML] Antarctic marine bacteria as a source of anti-biofilm molecules to combat ESKAPE pathogens

M Artini, R Papa, G Vrenna, M Trecca, I Paris… - Antibiotics, 2023 - mdpi.com
The ESKAPE pathogens, including bacteria such as Enterococcus faecium, Staphylococcus
aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and …

[HTML][HTML] Revisiting ESKAPE Pathogens: Virulence, resistance, and combating strategies focusing on quorum sensing

P Venkateswaran, S Vasudevan, H David… - Frontiers in cellular …, 2023 - frontiersin.org
The human–bacterial association is long-known and well-established in terms of both
augmentations of human health and attenuation. However, the growing incidents of …

[HTML][HTML] Antimicrobial and antibiofilm effects of essential fatty acids against clinically isolated vancomycin-resistant Enterococcus faecium

M Wei, P Wang, T Li, Q Wang, M Su, L Gu… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Enterococcus faecium is a leading cause of hospital-acquired infections, which
has become a serious public health concern. The increasing incidence of vancomycin …

[HTML][HTML] Characterization of the dispirotripiperazine derivative PDSTP as antibiotic adjuvant and antivirulence compound against Pseudomonas aeruginosa

A Bonacorsi, G Trespidi, VC Scoffone, S Irudal… - Frontiers in …, 2024 - frontiersin.org
Pseudomonas aeruginosa is a major human pathogen, able to establish difficult-to-treat
infections in immunocompromised and people with cystic fibrosis (CF). The high rate of …

Antimicrobial hydrogels incorporating nanoselenium@ reduced graphene oxide nanocomposites for biofilm inhibition

D Garg, V Kumar, MM SS, A Sachdev… - New Journal of Chemistry, 2024 - pubs.rsc.org
The growing prevalence of antibiotic-resistant bacterial strains is reducing the efficacy of
conventional treatments for bacterial infections and complicating the issue of biofilm …